Wang Xiao, Zhang Jiao-Zhen, Zhou Jin-Chuan, Shen Tao, Lou Hong-Xiang
Department of Natural Products Chemistry, Key Lab of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China.
Department of Natural Products Chemistry, Key Lab of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China.
Fitoterapia. 2016 Mar;109:1-7. doi: 10.1016/j.fitote.2015.11.023. Epub 2015 Nov 30.
Two new ent-prenylaromadendrane-type diterpenoids, diplotaxifols A (1) and B (2), a new ent-eudesmol, ent-eudesma-4(15),11(13)-dien-6α,12-diol (3), eight new eudesmanolides enantiomers (4-11) of the corresponding compounds from higher plants along with four known ent-eudesmanolides (12-15) were isolated from the 95% EtOH extract of Chinese liverwort Diplophyllum taxifolium. Their structures were elucidated on the basis of MS, NMR and IR spectral data, and confirmed by single-crystal X-ray diffraction analysis. The quinone reductase-inducing activity of the compounds was evaluated.
从中国苔类植物鳞叶叶苔的95%乙醇提取物中分离得到两个新的对映-异戊烯基芳香二萜类化合物，双叶叶苔醇A（1）和双叶叶苔醇B（2），一个新的对映-桉叶醇，对映-桉叶-4(15),11(13)-二烯-6α,12-二醇（3），八个来自高等植物相应化合物的新的桉叶烷内酯对映体（4-11）以及四个已知的对映-桉叶烷内酯（12-15）。基于质谱、核磁共振和红外光谱数据阐明了它们的结构，并通过单晶X射线衍射分析得到证实。对这些化合物的醌还原酶诱导活性进行了评估。
