Hollenbeck James E
Indiana University Southeast, New Albany, IN 47150, United States.
Infect Genet Evol. 2016 Mar;38:44-46. doi: 10.1016/j.meegid.2015.12.002. Epub 2015 Dec 2.
Most significant change in the evolution of the influenza virus is the rapid growth of the Concentrated Animal Feeding Operations (CAFOs) on a global scale. These industrial agricultural operations have the potential of housing thousands of animals in a relatively small area. Emerging Infectious Diseases (EIDs) event can be considered as a shift in the pathogen-host-environment interplay characteristics described by Engering et al. (2013). These changes in the host-environment and the disease ecology are key to creating novel transmission patterns and selection of novel pathogens with a modification of genetic traits. With the development of CAFOs throughout the world, the need for training of animal caretakers to observe, identify, treat, vaccinate and cull if necessary is important to safeguard public health. The best defense against another pandemic of Emerging Infectious Diseases (EIDs) is the constant monitoring of the livestock and handlers of CAFOs and the live animal markets. These are the most likely epicenter of the next pandemic.
流感病毒演变过程中最显著的变化是全球范围内集中式动物饲养场(CAFOs)的迅速发展。这些工业化农业经营场所能够在相对较小的区域内容纳数千只动物。新发传染病(EIDs)事件可被视为病原体-宿主-环境相互作用特征的一种转变,正如恩格宁等人(2013年)所描述的那样。宿主-环境以及疾病生态的这些变化是创造新传播模式以及选择具有遗传特征改变的新病原体的关键。随着全球范围内集中式动物饲养场的发展,培训动物饲养员进行观察、识别、治疗、接种疫苗以及在必要时进行扑杀,对于保障公众健康至关重要。防范另一场新发传染病大流行的最佳防御措施是持续监测集中式动物饲养场的牲畜和饲养人员以及活体动物市场。这些地方最有可能成为下一次大流行的中心。