Rushton Paul R P, Elmalky Mahmoud, Tikoo Agnivesh, Basu Saumyajit, Cole Ashley A, Grevitt Michael P
Centre for Spinal Studies and Surgery, Queen's Medical Centre, Nottingham, NG7 2UH, UK.
Faculty of Medicine, Menoufia University, Al Minufya, Egypt.
Eur Spine J. 2016 Oct;25(10):3324-3330. doi: 10.1007/s00586-015-4335-x. Epub 2015 Dec 10.
Determine impact of metal density on curve correction and costs in thoracic adolescent idiopathic scoliosis (AIS). Ascertain if increased metal density is required for larger or stiffer curves.
Multicentre retrospective case series of patients with Lenke 1-2 AIS treated with single-stage posterior only surgery using a standardized surgical technique; constructs using >80 % screws with variable metal density. All cases had >2-year follow up. Outcomes measures included coronal and sagittal radiographic outcomes, metal density (number of instrumented pedicles vs total available), fusion length and cost.
106 cases included 94 female. 78 Lenke 1. Mean age 14 years (9-26). Mean main thoracic (MT) Cobb angle 63° corrected to 22° (66 %). No significant correlations were present between metal density and: (a) coronal curve correction rates of the MT (r = 0.13, p = 0.19); (b) lumbar curve frontal correction (r = -0.15, p = 0.12); (c) correction index in MT curve (r = -0.10, p = 0.32); and (d) correction index in lumbar curve (r = 0.11, p = 0.28). Metal density was not correlated with change in thoracic kyphosis (r = 0.22, p = 0.04) or lumbosacral lordosis (r = 0.27, p = 0.01). Longer fusions were associated with greater loss of thoracic kyphosis (r = -0.31, p = 0.003). Groups differing by preoperative curve size and stiffness had comparable corrections with similar metal density. The pedicle screw cost represented 21-29 % of overall cost of inpatient treatment depending on metal density.
Metal density affects cost but not the coronal and sagittal correction of thoracic AIS. Neither larger nor stiffer curves necessitate high metal density.
确定金属密度对青少年特发性脊柱侧凸(AIS)胸椎侧弯矫正及费用的影响。确定对于更大或更僵硬的侧弯是否需要增加金属密度。
多中心回顾性病例系列研究,纳入采用标准化手术技术仅行单阶段后路手术治疗的Lenke 1-2型AIS患者;使用金属密度可变且螺钉使用率>80%的内固定装置。所有病例均随访超过2年。观察指标包括冠状面和矢状面影像学结果、金属密度(置入椎弓根螺钉数量与可用椎弓根总数之比)、融合长度和费用。
106例患者中94例为女性。78例为Lenke 1型。平均年龄14岁(9-26岁)。主胸弯(MT)平均Cobb角63°,矫正至22°(矫正率66%)。金属密度与以下各项之间无显著相关性:(a)MT冠状面侧弯矫正率(r = 0.13,p = 0.19);(b)腰椎侧弯额状面矫正(r = -0.15,p = 0.12);(c)MT弯矫正指数(r = -0.10,p = 0.32);以及(d)腰椎弯矫正指数(r = 0.11,p = 0.28)。金属密度与胸椎后凸变化(r = 0.22,p = 0.04)或腰骶前凸变化(r = 0.27,p = 0.01)无关。更长的融合与更大的胸椎后凸丢失相关(r = -0.31,p = 0.003)。术前侧弯大小和僵硬程度不同的组在金属密度相似的情况下矫正效果相当。根据金属密度,椎弓根螺钉费用占住院治疗总费用的21%-29%。
金属密度影响费用,但不影响AIS胸椎侧弯的冠状面和矢状面矫正。更大或更僵硬的侧弯均无需高金属密度。