Silva Amílcar B T, Capingana Daniel P, Magalhães Pedro, Molina Maria Del Carmen B, Baldo Marcelo P, Mill José Geraldo
Department of Physiological Sciences, Federal University of Espírito Santo, Espírito Santo, Brazil.
Department of Physiological Sciences, Medical School of the Agostinho Neto University, Luanda, Angola.
J Clin Hypertens (Greenwich). 2016 Aug;18(8):725-32. doi: 10.1111/jch.12739. Epub 2015 Dec 12.
Carotid-femoral pulse wave velocity (PWV) has been used as the gold standard method to estimate arterial stiffness. However, its use in clinical practice is still limited because reference values for specific groups, such as black children, remain unknown. The authors aimed to investigate predictors and to propose preliminary reference values of PWV in this population. Prepubertal schoolchildren (N=157; mean age, 9.36±1.41 year) from Luanda (Angola) with normal blood pressure values and without obesity were included. Mean PWV was 5.73±0.68 m/s, with no difference between the sexes. Univariate regression analysis showed a significant (P<.05) positive correlation between PWV and height, age, body weight, lean body weight, and blood pressure. In multivariate analysis, however, only height remained an independent predictor of PWV [PWV=0.018×height (cm)+3.230]. Curves of PWV percentiles as a function of height are proposed, thus identifying normal PWV in black children.
颈股脉搏波速度(PWV)已被用作评估动脉僵硬度的金标准方法。然而,由于特定群体(如黑人儿童)的参考值仍然未知,其在临床实践中的应用仍然有限。作者旨在研究预测因素,并提出该人群中PWV的初步参考值。纳入了来自罗安达(安哥拉)的血压正常且无肥胖的青春期前学龄儿童(N = 157;平均年龄,9.36±1.41岁)。平均PWV为5.73±0.68米/秒,男女之间无差异。单变量回归分析显示PWV与身高、年龄、体重、去脂体重和血压之间存在显著(P<0.05)正相关。然而,在多变量分析中,只有身高仍然是PWV的独立预测因素[PWV = 0.018×身高(厘米)+ 3.230]。提出了PWV百分位数随身高变化的曲线,从而确定黑人儿童的正常PWV。