Nakamura Jiro, Kamiya Hideki
Nihon Rinsho. 2015 Dec;73(12):2044-50.
Diagnostic criteria of diabetic neuropathy that can be easily used at bedsides and have international consensus have not been established. The most important therapeutic strategy is to maintain strict glycemic control. In addition, treatment with an aldose reductase inhibitor that is innovated from the viewpoint of the pathogenesis of diabetic neuropathy would be useful for preventing the progression of diabetic neuropathy. For painful diabetic neuropathy, pregabalin and duloxetine effectively relieve the pain, and contribute to the improvement of the quality of life.
目前尚未建立可在床边轻松使用且具有国际共识的糖尿病神经病变诊断标准。最重要的治疗策略是维持严格的血糖控制。此外，从糖尿病神经病变发病机制角度研发的醛糖还原酶抑制剂治疗，对于预防糖尿病神经病变的进展将是有益的。对于疼痛性糖尿病神经病变，普瑞巴林和度洛西汀可有效缓解疼痛，并有助于改善生活质量。
