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颈胸段和腰段脊髓神经鞘瘤的手术方法及疗效

Surgical methods and efficacies for cervicothoracolumbar spinal schwannoma.

作者信息

Deng Qiang, Tian Zheng, Sheng Weibin, Guo Hailong, Dan Mai Er

机构信息

Department of Spinal Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uyghur Autonomous Region 830054, P.R. China.

出版信息

Exp Ther Med. 2015 Dec;10(6):2023-2028. doi: 10.3892/etm.2015.2803. Epub 2015 Oct 15.

DOI:10.3892/etm.2015.2803
PMID:26668590
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4665202/
Abstract

The aim of this study was to investigate the surgical methods and efficacies for cervicothoracolumbar spinal schwannoma (CSS). A total of 52 patients who had undergone treatment for schwannoma were retrospectively analyzed. Two methods were employed for the surgical resection of the thoracic and lumbar schwannomas: Type I (posterior midline approach semi-laminectomy with tumor resection and internal fixation with pedicle screws) was used in 24 cases, and type II (posterior midline approach laminectomy with tumor resection and internal fixation with pedicle screws) was used in 26 cases. Two cases of giant cervical schwannoma were treated via anterior-posterior combined surgery. Histopathological examination confirmed the diagnosis of schwannoma in all cases (n=52). The clinical status of the patients was evaluated pre- and postoperatively using the visual analog scale, Oswestry Disability Index and Japanese Orthopedic Association scale, and the scores associated with the two types of surgical method were compared. Within the follow-up period, which lasted between 6 months and 3 years, no recurrence was detected, and such preoperative symptoms as radicular pain and spinal dysfunction were improved significantly. The numbness and hyperesthesia were relieved to different extents. In conclusion, methods of exposing and surgically treating CSS should be selected according to the growth site of the schwannoma in order to reduce the blood loss and surgery duration and to improve the surgical safety.

摘要

本研究旨在探讨颈胸段及胸腰段脊髓神经鞘瘤(CSS)的手术方法及疗效。对52例接受神经鞘瘤治疗的患者进行回顾性分析。胸腰段神经鞘瘤的手术切除采用两种方法:I型(后正中入路半椎板切除肿瘤并椎弓根螺钉内固定)24例,II型(后正中入路全椎板切除肿瘤并椎弓根螺钉内固定)26例。2例巨大颈段神经鞘瘤采用前后联合手术治疗。所有病例(n = 52)经组织病理学检查确诊为神经鞘瘤。采用视觉模拟评分法、Oswestry功能障碍指数和日本矫形外科学会评分法对患者术前及术后的临床状况进行评估,并比较两种手术方法的评分。在6个月至3年的随访期内,未发现复发,术前神经根性疼痛和脊髓功能障碍等症状明显改善。麻木和感觉过敏在不同程度上得到缓解。总之,应根据神经鞘瘤的生长部位选择CSS的显露和手术治疗方法,以减少出血量和手术时间,提高手术安全性。

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