Li Haoxin, Doucet Brandon, Flewelling Andrew J, Jean Stéphanie, Webster Duncan, Robichaud Gilles A, Johnson John A, Gray Christopher A
Nat Prod Commun. 2015 Oct;10(10):1641-2.
Antimycobacterial extracts of a Penicillium sp. (isolate HL4-159-41B) and a Coniothyrium sp. (isolate HL6-097-027B) isolated from the rhizomes of the Canadian medicinal plant Aralia nudicaulis were found to contain palitantin (1) and botrallin (2), craterellin C (3), mycosporulone (4), spiromassaritone (5), and massarigenin D (6) respectively. Bioassays against Mycobacterium tuberculosis H37Ra revealed that 1 - 4 possess moderate antimycobacterial activity.
从加拿大药用植物短梗五加的根茎中分离出的一株青霉菌(菌株HL4-159-41B)和一株盾壳霉属真菌(菌株HL6-097-027B)的抗分枝杆菌提取物,分别被发现含有帕利坦汀(1)和波曲菌素(2)、小皮伞菌素C(3)、枝孢菌酮(4)、螺马萨里酮(5)和马萨里菌素D(6)。针对结核分枝杆菌H37Ra的生物测定表明,1-4具有中等抗分枝杆菌活性。