Stroke Center &Department of Neurology, Kings County Hospital Center &The State University of New York Downstate Medical Center, 451 Clarkson Avenue, Brooklyn, New York, NY-11203, USA.
Nat Rev Neurol. 2016 Jan;12(1):8-9. doi: 10.1038/nrneurol.2015.231. Epub 2015 Dec 16.
In Europe, use of intravenous tissue plasminogen activator (tPA) in patients older than 80 years is discouraged because these patients have been excluded from certain past clinical trials. A new retrospective, observational study shows that tPA can substantially improve functional outcome after ischaemic stroke in patients aged 80–89 years.
在欧洲，不鼓励 80 岁以上的患者使用静脉内组织型纤溶酶原激活剂（tPA），因为这些患者被排除在某些过去的临床试验之外。一项新的回顾性观察研究表明，tPA 可显著改善 80-89 岁缺血性脑卒中患者的功能预后。
