Saxena Divya, Saha Suparna Ganguly, Saha Mainak Kanti, Dubey Sandeep, Khatri Margie
Department of Conservative Dentistry and Endodontics, College of Dental Science and Hospital, Indore, Madhya Pradesh, India.
Indian J Dent Res. 2015 Sep-Oct;26(5):524-7. doi: 10.4103/0970-9290.172080.
Sodium hypochlorite is the most widely used irrigant in endodontic practice, but it has various disadvantages. Literature has shown that herbal products such as Propolis, Azadirachta indica (AI), Triphala, Curcuma longa, and Morinda citrifolia (MC) possess good antimicrobial properties and thus can be used as potential endodontic irrigants.
To evaluate and compare the antimicrobial activity of five herbal extracts, i.e., Propolis, AI, Triphala, C. longa, and MC with that of 2.5% sodium hypochlorite against Enterococcus faecalis.
E. faecalis American Type Culture Collection 21292 was inoculated onto brain heart infusion agar plate. Discs impregnated with herbal medicaments were placed on the inoculated plates and incubated at 37°C aerobically for 24 h and growth inhibition zones were measured.
Mean zone of inhibition in descending order was found as sodium hypochlorite > Propolis > AI > Triphala > C. longa = MC > ethanol. Statistical analysis was performed using one-way analysis of variance which showed a significant difference in the zone of inhibition of sodium hypochlorite and Propolis (P < 0.001).
Propolis showed highest zone of inhibition among all the herbal extracts next to sodium hypochlorite.
Propolis and AI have significant antimicrobial activity against E. faecalis.
次氯酸钠是牙髓病治疗中使用最广泛的冲洗剂，但它有各种缺点。文献表明，诸如蜂胶、印楝、三果木、姜黄和海巴戟等草药产品具有良好的抗菌特性，因此可作为潜在的牙髓冲洗剂。
评估并比较五种草药提取物（即蜂胶、印楝、三果木、姜黄和海巴戟）与2.5%次氯酸钠对粪肠球菌的抗菌活性。
将粪肠球菌美国典型培养物保藏中心21292接种到脑心浸液琼脂平板上。将浸有草药药剂的圆片置于接种平板上，于37℃需氧培养24小时，测量抑菌圈。
抑菌圈平均大小由大到小依次为次氯酸钠>蜂胶>印楝>三果木>姜黄=海巴戟>乙醇。采用单因素方差分析进行统计分析，结果显示次氯酸钠和蜂胶的抑菌圈有显著差异（P<0.001）。
在所有草药提取物中，蜂胶的抑菌圈仅次于次氯酸钠，最大。
蜂胶和印楝对粪肠球菌具有显著的抗菌活性。
