Karkare Swati Ramesh, Ahire Nivedita Pramod, Khedkar Smita Uday
Department of Preventive Dentistry, MGV's KBH Dental College and Hospital, Nashik, Maharashtra, India.
J Indian Soc Pedod Prev Dent. 2015 Oct-Dec;33(4):274-8. doi: 10.4103/0970-4388.165658.
Enterococcus faecalis are the most resistant and predominant microorganisms recovered from root canals of teeth where previous treatment has failed. Over the past decade, interest in drugs derived from medicinal plants has markedly increased. In dentistry, phytomedicines has been used as an anti-inflammatory, antibiotic, analgesic, sedative, and also as an endodontic irrigant. In endodontics, because of the cytotoxic reactions of most of the commercial intracanal medicaments and their inability to eliminate bacteria completely from dentinal tubules, the trend is shifting toward use of biologic medication extracted from natural plants.
To compare the antimicrobial efficacy of newer irrigating agents which would probably be as effective or more and at the same time less irritating to the tissues than sodium hypochlorite (NaOCl). The objective of this study was to compare the antimicrobial activity of saturated and diluted (1:1) hydroalcoholic extract of Aloe vera, garlic, and 5% NaOCl against E. faecalis using the commonly used agar diffusion method.
Saturated hydroalcoholic extract of A. vera showed the highest zone of inhibition against E. faecalis. NaOCl, which is considered as gold standard, also showed higher zones of inhibition.
粪肠球菌是从先前治疗失败的牙齿根管中分离出的最具耐药性且占主导地位的微生物。在过去十年中,对源自药用植物的药物的兴趣显著增加。在牙科领域,植物药已被用作抗炎药、抗生素、镇痛药、镇静剂,还用作根管冲洗剂。在牙髓病学中,由于大多数市售根管内药物具有细胞毒性反应,且无法从牙本质小管中完全清除细菌,因此趋势正转向使用从天然植物中提取的生物药物。
比较新型冲洗剂的抗菌效果,这些冲洗剂可能与次氯酸钠(NaOCl)一样有效或更有效,同时对组织的刺激性更小。本研究的目的是使用常用的琼脂扩散法,比较芦荟、大蒜的饱和及稀释(1:1)水醇提取物和5% NaOCl对粪肠球菌的抗菌活性。
芦荟的饱和水醇提取物对粪肠球菌显示出最高的抑菌圈。被视为金标准的NaOCl也显示出较高的抑菌圈。