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貌似健康的年轻成年人中的高血压前期:血红蛋白水平的发生率及影响

Pre-Hypertension in Apparently Healthy Young Adults: Incidence and Influence of Haemoglobin Level.

作者信息

Senthil Sunandha, Krishndasa Subbalakshmi Narasajjana

机构信息

MBBS Student, Kasturba Medical College, Manipal University Mangalore , Karnataka, India .

Associate Professor, Department of Physiology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .

出版信息

J Clin Diagn Res. 2015 Nov;9(11):CC10-2. doi: 10.7860/JCDR/2015/14970.6847. Epub 2015 Nov 1.

Abstract

INTRODUCTION

Prehypertension is a precursor of clinical hypertension and consequently of the cardiovascular disease. Recent studies have found positive correlation between Haemoglobin Level (Hb) and Blood Pressure (BP). But the presumed association between Hb and BP has not been investigated in healthy young adults.

AIM

This study aimed to estimate the incidence of prehypertension and the influence of Hb level on BP in healthy young adults.

MATERIALS AND METHODS

This was a cross-sectional study done in 84 apparently healthy undergraduate medical students aged between 18-23 years, of either sex. In study subjects, BP and haemoglobin content was measured. Prehypertension was defined as BP levels of 120 to 139/80 to 89 mm Hg. Statistical analysis was done by unpaired t-test and Pearson correlation Coefficient tests.

RESULTS

Incidence of prehypertension was 50%. In 24% of the study subjects both systolic and diastolic BP was in prehypertensive state. In another 26% of study subjects only systolic BP was above normal. There was positive correlation between systolic BP and Hb level (p = 0.0015).

CONCLUSION

High incidence of prehypertension especially systolic prehypertension prevails inapparently healthy medical undergraduate students. In them, positive correlation between Hb and systolic BP persists.

摘要

引言

高血压前期是临床高血压的先兆,因此也是心血管疾病的先兆。最近的研究发现血红蛋白水平(Hb)与血压(BP)之间存在正相关。但在健康的年轻成年人中,尚未对Hb与BP之间的假定关联进行研究。

目的

本研究旨在评估健康年轻成年人中高血压前期的发病率以及Hb水平对血压的影响。

材料与方法

这是一项横断面研究,研究对象为84名年龄在18至23岁之间、性别不限的本科医学生,他们看起来均健康。对研究对象测量血压和血红蛋白含量。高血压前期定义为血压水平为120至139/80至89毫米汞柱。采用非配对t检验和Pearson相关系数检验进行统计分析。

结果

高血压前期的发病率为50%。在24%的研究对象中,收缩压和舒张压均处于高血压前期状态。在另外26%的研究对象中,仅收缩压高于正常水平。收缩压与Hb水平之间存在正相关(p = 0.0015)。

结论

在看似健康的本科医学生中,高血压前期尤其是收缩期高血压前期的发病率较高。在他们当中,Hb与收缩压之间持续存在正相关。

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