Piskunowicz Maciej, Kosiak Wojciech, Batko Tomasz, Adamkiewicz-Drożyńska Elżbieta, Szarmach Arkadiusz
Zakład Radiologii, Gdański Uniwersytet Medyczny, Gdańsk, Polska.
Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii Dziecięcej, Gdański Uniwersytet Medyczny, Gdańsk, Polska.
J Ultrason. 2013 Dec;13(55):438-45. doi: 10.15557/JoU.2013.0047. Epub 2013 Dec 30.
The lack of registration of ultrasound contrast agents for use in patients below the age of 18 is a significant limitation of their usage. Despite this, examinations with the use of contrast agents are conducted in numerous centers, mainly as part of the diagnostic process of vesicoureteral reflux. Examinations after an intravenous administration of contrast agents are conducted rarely. The reason for this is not only the lack of registration, but also the lack of studies on their safety profile in paediatric patients or no guidelines concerning the dosage. It seems that imaging with the use of such agents could help solve certain clinical problems when other diagnostic methods fail. The paper presents selected cases of pediatric patients treated in oncological departments, in whom the examination with the use of ultrasound contrast agents had a considerable influence on the diagnostic and therapeutic process.
18岁以下患者使用超声造影剂缺乏注册登记，这是其应用的一个重大限制。尽管如此，许多中心仍在使用造影剂进行检查，主要是作为膀胱输尿管反流诊断过程的一部分。静脉注射造影剂后的检查很少进行。其原因不仅是缺乏注册登记，还在于缺乏关于儿科患者安全性的研究或没有关于剂量的指南。当其他诊断方法失败时，使用此类造影剂进行成像似乎有助于解决某些临床问题。本文介绍了肿瘤科室治疗的部分儿科患者病例，其中使用超声造影剂的检查对诊断和治疗过程产生了重大影响。
