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先天性和获得性颈部、腹部和盆腔局灶性病变的超声造影诊断:影像学研究。

Diagnosis of congenital and acquired focal lesions in the neck, abdomen, and pelvis with contrast-enhanced ultrasound: a pictorial essay.

机构信息

School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Division of Pediatric Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.

出版信息

Eur J Pediatr. 2018 Oct;177(10):1459-1470. doi: 10.1007/s00431-018-3197-8. Epub 2018 Jul 3.

DOI:10.1007/s00431-018-3197-8
PMID:29971555
Abstract

UNLABELLED

Contrast-enhanced ultrasound (CEUS) is a versatile imaging modality that improves the diagnostic potential of conventional ultrasound. It allows for portable imaging at the bedside. In this paper, we illustrate how CEUS can be used in evaluating several focal lesions in the pediatric population, including liver hemangioma, telangiectasias, splenic hamartomas, and bladder lesions. We describe the ultrasound findings and contrast enhancement patterns associated with these lesions. Findings are correlated with MRI, CT, and/or pathology when available. This paper demonstrates the value of CEUS in improving characterization of many focal lesions in the pediatric population.

CONCLUSION

CEUS is a valuable bedside technique for use in the pediatric population to evaluate focal lesions in various organs, and will allow for safe, more efficient diagnostic imaging. What is Known: • CEUS offers many advantages over CT and MRI and is underutilized in the United States. • It is only FDA approved for vesicoureteral reflux and liver in the pediatric population. However, off label uses are well described. What is New: • This pictorial essay describes ultrasound findings and contrast enhancement patterns associated with liver hemangioma, liver telangiectasia, splenic hamartoma, hemorrhagic ovarian cyst, urachal remnant, spinning top urethras, and kaposiform hemangioendothelioma. • We demonstrate the utility of CEUS in expanding the diagnostic potential of conventional ultrasound.

摘要

未加说明

对比增强超声(CEUS)是一种多功能成像方式,可提高常规超声的诊断潜力。它允许在床边进行便携式成像。在本文中,我们举例说明了 CEUS 如何用于评估儿科人群中的几种局灶性病变,包括肝血管瘤、毛细血管扩张症、脾错构瘤和膀胱病变。我们描述了与这些病变相关的超声表现和对比增强模式。在有条件的情况下,将结果与 MRI、CT 和/或病理学进行了相关性比较。本文证明了 CEUS 在提高儿科人群中许多局灶性病变特征方面的价值。

结论

CEUS 是一种在儿科人群中用于评估各种器官局灶性病变的有价值的床边技术,将允许进行更安全、更高效的诊断成像。

已知

  1. CEUS 比 CT 和 MRI 具有许多优势,在美国的应用不足。

  2. 它仅在美国食品和药物管理局(FDA)批准用于儿科人群的膀胱输尿管反流和肝脏。然而,其在其他方面的应用也有很好的描述。

新内容

  1. 本图片文章描述了肝血管瘤、肝毛细血管扩张症、脾错构瘤、出血性卵巢囊肿、脐尿管残余、旋转阴茎尿道和卡波西样血管内皮细胞瘤相关的超声表现和对比增强模式。

  2. 我们展示了 CEUS 在扩大常规超声诊断潜力方面的实用性。

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Diagnosis of congenital and acquired focal lesions in the neck, abdomen, and pelvis with contrast-enhanced ultrasound: a pictorial essay.先天性和获得性颈部、腹部和盆腔局灶性病变的超声造影诊断:影像学研究。
Eur J Pediatr. 2018 Oct;177(10):1459-1470. doi: 10.1007/s00431-018-3197-8. Epub 2018 Jul 3.
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Practical advantages of contrast-enhanced ultrasound in abdominopelvic radiology.对比增强超声在腹盆部放射学中的实用优势。
Abdom Radiol (NY). 2018 Apr;43(4):998-1012. doi: 10.1007/s00261-017-1442-7.
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Applications of contrast-enhanced ultrasound in the pediatric abdomen.超声造影在儿科腹部的应用。
Abdom Radiol (NY). 2018 Apr;43(4):948-959. doi: 10.1007/s00261-017-1315-0.
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Contrast-enhanced ultrasound versus MS-CT in blunt abdominal trauma.腹部钝性创伤中超声造影与多层螺旋CT的比较
Clin Hemorheol Microcirc. 2008;39(1-4):155-69.
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Contrast-Enhanced Ultrasound (CEUS) for the characterization of focal liver lesions - prospective comparison in clinical practice: CEUS vs. CT (DEGUM multicenter trial). Parts of this manuscript were presented at the Ultrasound Dreiländertreffen 2008, Davos.超声造影(CEUS)用于肝脏局灶性病变的特征性诊断——临床实践中的前瞻性比较:CEUS与CT(德国超声医学与工程学会多中心试验)。本手稿的部分内容曾在2008年于达沃斯举行的三国超声会议上展示。
Ultraschall Med. 2009 Aug;30(4):383-9. doi: 10.1055/s-0028-1109673. Epub 2009 Aug 17.
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Single-center study: The diagnostic performance of contrast-enhanced ultrasound (CEUS) for assessing focal splenic lesions compared to CT and MRI.单中心研究:与 CT 和 MRI 相比,超声造影(CEUS)评估局灶性脾脏病变的诊断性能。
Clin Hemorheol Microcirc. 2019;73(1):65-71. doi: 10.3233/CH-199204.
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Contrast enhancement ultrasound application in focal liver lesions characterization: a retrospective study about guidelines application (SOCEUS-CEUS survey).超声造影在肝脏局灶性病变特征诊断中的应用:一项关于指南应用的回顾性研究(SOCEUS-CEUS调查)
J Ultrasound. 2015 Nov 2;19(2):99-106. doi: 10.1007/s40477-015-0185-y. eCollection 2016.
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Incidentally detected splenic lesions in ultrasound: does contrast-enhanced ultrasonography improve the differentiation of benign hemangioma/hamartoma from malignant lesions?偶然发现的超声脾脏病变:增强超声造影是否能改善良恶性病变的鉴别诊断?
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A Milestone: Approval of CEUS for Diagnostic Liver Imaging in Adults and Children in the USA.一个里程碑:在美国,超声造影剂被批准用于成人和儿童肝脏诊断成像。
Ultraschall Med. 2016 Jun;37(3):229-32. doi: 10.1055/s-0042-107411. Epub 2016 Jun 8.
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Abdom Radiol (NY). 2018 Dec;43(12):3279-3287. doi: 10.1007/s00261-018-1608-y.

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Diagnostics (Basel). 2025 Jul 1;15(13):1680. doi: 10.3390/diagnostics15131680.
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Contrast-Enhanced Ultrasound as a Main Radiological Diagnostic Method for Primary Liver Neoplasms and Hemangiomas.超声造影作为原发性肝脏肿瘤和肝血管瘤的主要影像学诊断方法
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本文引用的文献

1
Contrast-enhanced US Assessment of Focal Liver Lesions in Children.超声造影评估儿童肝脏局灶性病变
Radiographics. 2017 Oct;37(6):1632-1647. doi: 10.1148/rg.2017170073.
2
Novel Contrast-Enhanced Ultrasound Evaluation in Neonatal Hypoxic Ischemic Injury: Clinical Application and Future Directions.新生儿缺氧缺血性损伤的新型超声造影评估:临床应用与未来方向
J Ultrasound Med. 2017 Nov;36(11):2379-2386. doi: 10.1002/jum.14289. Epub 2017 Jun 26.
3
Intravenous and Intracavitary Use of Contrast-Enhanced Ultrasound in the Evaluation and Management of Complicated Pediatric Pneumonia.
儿科影像学的高级超声技术。
Pediatrics. 2019 Mar;143(3). doi: 10.1542/peds.2018-2609.
超声造影剂在儿科复杂性肺炎评估与治疗中的静脉及腔内应用
J Ultrasound Med. 2017 Sep;36(9):1943-1954. doi: 10.1002/jum.14269. Epub 2017 Jun 19.
4
Utility of quantitative contrast-enhanced ultrasound for the prediction of extracapsular extension in papillary thyroid carcinoma.定量对比增强超声在预测甲状腺乳头状癌囊外侵犯中的应用。
Sci Rep. 2017 May 3;7(1):1472. doi: 10.1038/s41598-017-01650-2.
5
Safety With Echocardiographic Contrast Agents.超声心动图造影剂的安全性。
Circ Cardiovasc Imaging. 2017 Apr;10(4). doi: 10.1161/CIRCIMAGING.116.005459.
6
Imaging findings of Kaposiform Hemangioendothelioma in children.儿童卡波西样血管内皮瘤的影像学表现。
Eur J Radiol. 2017 Jan;86:198-205. doi: 10.1016/j.ejrad.2016.11.015. Epub 2016 Nov 10.
7
Retrospective Analysis of the Safety and Cost Implications of Pediatric Contrast-Enhanced Ultrasound at a Single Center.单中心小儿超声造影安全性及成本影响的回顾性分析
AJR Am J Roentgenol. 2017 Feb;208(2):446-452. doi: 10.2214/AJR.16.16700. Epub 2016 Dec 13.
8
Quantitative contrast-enhanced ultrasonography for the differential diagnosis of endometrial hyperplasia and endometrial neoplasms.定量对比增强超声检查在子宫内膜增生和子宫内膜肿瘤鉴别诊断中的应用
Oncol Lett. 2016 Nov;12(5):3763-3770. doi: 10.3892/ol.2016.5206. Epub 2016 Sep 29.
9
Imaging of the Urachus: Anomalies, Complications, and Mimics.脐尿管的影像学检查:异常、并发症及类似疾病
Radiographics. 2016 Nov-Dec;36(7):2049-2063. doi: 10.1148/rg.2016160062.
10
Enhancing the role of paediatric ultrasound with microbubbles: a review of intravenous applications.增强微泡在儿科超声中的作用:静脉应用综述
Br J Radiol. 2017 Jan;90(1069):20160556. doi: 10.1259/bjr.20160556. Epub 2016 Sep 26.