Lakshmi Chembolli, Krishnaswamy Gayathri
Department of Dermatology, PSG Hospitals and PSGIMSR, Coimbatore, Tamil Nadu, India.
Indian J Dermatol. 2015 Nov-Dec;60(6):578-83. doi: 10.4103/0019-5154.169129.
Q-switched neodymium: yttrium aluminum garnet (Nd: YAG) laser at a wavelength of 1064 nm primarily targets dermal melanin and black tattoo ink. Recent studies have shown that this laser is effective in treating black tattoos. There are few studies conducted in India for the same.
The aim was to assess the effectiveness of Q-switched Nd: YAG laser (QSNYL) in the treatment of blue-black tattoos following 3 treatment sessions.
This study, a prospective interventional study included a total of 12 blue-black tattoos. Following informed consent for the procedure, as well as for photographs, a questionnaire was administered, and improvement perceived by the patient was recorded. In addition, global assessment score (GAS) by a blinded physician was also recorded. Photographs were taken at baseline and at every follow-up. Each patient underwent three treatment sessions with 1064 nm QSNYL at 4-6 weekly intervals. Fluences ranged from 1.8 to 9 J/cm(2). The follow-up was done monthly for 4 months from the first treatment session. The response was assessed by patient assessment (PA) and GAS by comparing photographs.
After three treatment sessions, although no patient achieved clearance, most patients showed good response with few adverse effects. An average of 64.1% (GAS) and 54.2% (PA) improvement was observed in 12 tattoos. Tattoos more than 10-year-old showed quicker clearing than those less than 10-year-old. Amateur tattoos also showed a better response in comparison to professional tattoos.
Totally, 1064 nm QSNYL is safe and effective for lightening blue-black tattoos in pigmented Indian skin. All patients achieved near complete clearance following the continuation of treatment (an average of six sessions) although this was spaced at longer intervals.
波长为1064nm的调Q钕：钇铝石榴石（Nd：YAG）激光主要作用于真皮黑色素和黑色纹身墨水。近期研究表明，这种激光在治疗黑色纹身方面有效。在印度针对此开展的研究较少。
旨在评估调Q Nd：YAG激光（QSNYL）在进行3次治疗后对蓝黑色纹身的治疗效果。
本研究为前瞻性干预性研究，共纳入12例蓝黑色纹身。在获得手术及拍照的知情同意后，发放问卷，并记录患者感知到的改善情况。此外，还记录了由一名不知情的医生给出的整体评估得分（GAS）。在基线期和每次随访时拍照。每位患者接受3次治疗，使用1064nm的QSNYL，每隔4 - 6周进行一次。能量密度范围为1.8至9J/cm²。从第一次治疗开始，每月随访4个月。通过比较照片，由患者评估（PA）和GAS来评估反应。
经过3次治疗后，虽然没有患者实现纹身完全清除，但大多数患者反应良好，不良反应较少。在12例纹身中，平均观察到改善率为64.1%（GAS）和54.2%（PA）。超过10年的纹身比小于10年的纹身清除得更快。与专业纹身相比，业余纹身的反应也更好。
总体而言，1064nm的QSNYL对于印度有色人种皮肤中蓝黑色纹身的淡化是安全有效的。所有患者在继续治疗（平均6次）后虽间隔时间较长，但均实现了近乎完全清除。
