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1064纳米调Q掺钕钇铝石榴石激光治疗太田痣的特征回顾性研究

A Retrospective Study on the Characteristics of Treating Nevus of Ota by 1064-nm Q-switched Neodymium-doped Yttrium Aluminum Garnet Laser.

作者信息

Liu Yanting, Zeng Weihui, Geng Songmei

机构信息

Department of Dermatology, Northwest Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, PR China.

出版信息

Indian J Dermatol. 2016 May-Jun;61(3):347. doi: 10.4103/0019-5154.182470.

Abstract

BACKGROUND

The Q-switched neodymium-doped yttrium aluminum garnet (QS Nd:YAG) laser has a significant effect in treating nevus of Ota, but there is lack of a retrospective study about the characteristics of efficacy.

AIMS AND OBJECTIVES

To retrospectively analyze the correlation between the clinical characteristics and efficacy, complications, recurrence of QS Nd:YAG laser in treating nevus of Ota.

MATERIALS AND METHODS

One hundred and seventy-one Chinese patients (144 female, 27 male) of nevus of Ota were treated with the 1064-nm QS Nd:YAG laser. All cases were treated with fluencies of 4-8 J/cm(2) and a spot size of 2-4 mm. Clinical photographs were taken before every treatment and patients were followed up by their clinicians.

RESULTS

One hundred and forty-five patients (84.8%) acquired more than 75% improvement with an average of 4.6 sessions. The treatment effect has no significant correlation with sex (P > 0.05). The blue-black and brown lesions improved more than the light-brown (P < 0.05). Hyperpigmentation affected two (1.2%) of the patients and hypopigmentation affected one patient (0.6%). No other adverse effect was observed. Recurrence was seen in two patients (1.2%).

CONCLUSION

The 1064-nm QS Nd:YAG laser is effective with rare complications and recurrence in the treatment of nevus of Ota. The efficacy correlated with lesion color, which is meaningful to estimate the prognosis.

摘要

背景

调Q开关掺钕钇铝石榴石(QS Nd:YAG)激光治疗太田痣有显著效果,但缺乏关于疗效特征的回顾性研究。

目的

回顾性分析QS Nd:YAG激光治疗太田痣的临床特征与疗效、并发症及复发之间的相关性。

材料与方法

171例中国太田痣患者(144例女性,27例男性)接受1064nm QS Nd:YAG激光治疗。所有病例的能量密度为4 - 8J/cm²,光斑大小为2 - 4mm。每次治疗前拍摄临床照片,由临床医生对患者进行随访。

结果

145例患者(84.8%)改善率超过75%,平均治疗4.6次。治疗效果与性别无显著相关性(P > 0.05)。蓝黑色和棕色皮损的改善程度优于浅棕色皮损(P < 0.05)。2例患者(1.2%)出现色素沉着,1例患者(0.6%)出现色素减退。未观察到其他不良反应。2例患者(1.2%)复发。

结论

1064nm QS Nd:YAG激光治疗太田痣有效,并发症和复发少见。疗效与皮损颜色相关,对评估预后有意义。

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