扁平苔藓样天疱疮优先出现在既往瘢痕上：一种罕见的同位素现象实例。

Lichen Planus Pemphigoides Presenting Preferentially Over Preexisting Scars: A Rare Instance of Isotopic Phenomenon.

作者信息

Kumar Piyush, Savant Sushil S, Das Anupam, Hassan Shahid, Barman Panchami Deb

机构信息

Department of Dermatology, Katihar Medical College, Katihar, Bihar, India.

Department of Dermatology, Medical College and Hospital, Kolkata, Kolkata, West Bengal, India.

出版信息

Indian J Dermatol. 2015 Nov-Dec;60(6):596-9. doi: 10.4103/0019-5154.169133.

DOI:10.4103/0019-5154.169133

PMID:26677275

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4681200/

Abstract

An 18-year-old girl presented with multiple itchy hyperpigmented papules and plaques, along with tense blisters over the lower limbs and buttocks for last 3 months. These papules, plaques, and bullae were mostly localized to preexisting scars. The histopathological findings from papule and bulla were consistent with lichen planus (LP) and bullous pemphigoid, respectively. Direct immunofluorescence (DIF) of perilesional skin around bulla showed linear deposition of IgG and C3. Considering clinical, histopathological and DIF findings, diagnosis of LP pemphigoides (LPP) was made. The preferential localization of LPP lesions over preexisting scars was a very interesting finding in our case an extremely rare instance of the isotopic phenomenon.

摘要

一名18岁女孩在过去3个月里出现了多处瘙痒性色素沉着丘疹和斑块，同时下肢和臀部出现紧张性水疱。这些丘疹、斑块和大疱大多局限于既往瘢痕处。丘疹和大疱的组织病理学表现分别与扁平苔藓（LP）和大疱性类天疱疮一致。大疱周围皮损的直接免疫荧光（DIF）显示IgG和C3呈线状沉积。综合临床、组织病理学和DIF检查结果，诊断为扁平苔藓类天疱疮（LPP）。在我们的病例中，LPP皮损优先出现在既往瘢痕处是一个非常有趣的发现，这是同位素现象的一个极其罕见的实例。