Cancer Res Treat. 2003 Oct;35(5):460-4. doi: 10.4143/crt.2003.35.5.460.
Metastasis of breast cancer to the stomach is relatively uncommon and typically occurs in patients with disseminated diseases. This may cause difficulty in differentiating it from primary gastric carcinoma. The correct diagnosis of the primary source is important, since the treatment and prognosis of metastatic breast cancer is quite different from those of metastatic gastric cancer. Immunohistochemical staining with GCDFP-15 (gross cystic disease fluid protein-15) can be used to differentiate primary gastric carcinoma and gastric metastasis from breast cancer. We report two cases of gastric metastasis of breast cancer by describing their clinical course, illustrating the histologic findings, and showing the results of immunohistochemical staining with GCDFP-15.
乳腺癌转移至胃部相对少见，通常发生于有播散性疾病的患者。这可能使其与原发性胃癌难以区分。正确诊断原发灶非常重要，因为转移性乳腺癌的治疗和预后与转移性胃癌有很大不同。使用 GCDFP-15（巨大囊泡性疾病液体蛋白 15）免疫组织化学染色可用于区分原发性胃癌和来自乳腺癌的胃转移。我们通过描述其临床过程、展示组织学发现并展示 GCDFP-15 免疫组织化学染色的结果，报告了两例乳腺癌胃转移病例。
