Schjonsby H
Acta Med Scand Suppl. 1977;603:39-41.
Osteomalacia in a 80-year old woman with malabsorption due to the stagnant loop syndrome is reported. The osteomalacia was associated with bacterial overgrowth in the small intestine and increased bile salt deconjugation. Although the mechanism of osteomalacia in the stagnant loop syndrome remains uncertain, it is suggested that abnormal flora reduce the absorption of vitamin D by deconjugation of bile salts in the lumen of the small intestine.
报告了一名80岁患有因肠淤滞综合征导致吸收不良的女性患骨软化症的病例。该骨软化症与小肠细菌过度生长及胆盐去结合增加有关。尽管肠淤滞综合征中骨软化症的机制仍不确定,但提示异常菌群通过在小肠腔内使胆盐去结合而减少维生素D的吸收。