Clement D L
Department of Cardiology, University Hospital, Ghent, Belgium.
J Hypertens Suppl. 1989 May;7(3):S49-51.
A prospective multicentre study has been set up to examine the following primary questions: (1) Is there a better correlation between blood pressure and mortality, morbidity or organ damage when blood pressure is measured by ambulatory recordings rather than by the usual office method? (2) Is there a difference in the rates of mortality, morbidity and organ damage when treatment is guided by ambulatory values instead of by office values? The aim is to study 2000 patients with primary hypertension, aged 35-70 years, for 5 years. Ambulatory recordings will be made every 6 months. Treatment will be based at random on either office or ambulatory blood pressure readings at each centre.
一项前瞻性多中心研究已经启动，以探讨以下主要问题：（1）通过动态血压记录测量血压时，与采用常规诊室测量方法相比，血压与死亡率、发病率或器官损害之间是否存在更好的相关性？（2）以动态血压值而非诊室血压值为指导进行治疗时，死亡率、发病率和器官损害的发生率是否存在差异？目标是对2000例年龄在35至70岁之间的原发性高血压患者进行为期5年的研究。每6个月进行一次动态血压记录。每个中心将随机根据诊室或动态血压读数进行治疗。
