Leeder S R, Pengelly L D
Aust N Z J Med. 1977 Feb;7(1):78-87. doi: 10.1111/j.1445-5994.1977.tb03362.x.
Epidemiological information about the health consequences of ambient air pollution is adequate at present to set upper limits so that acute deterioration due to pollution can be prevented in patients with chronic lung disease. However, our knowledge is incomplete with respect to what is a safe chronic background level, particularly with regard to reducing and preventing the amount of chronic respiratory disease presently occurring. This review concentrates exclusively on sulphur dioxide and particulate pollution, although the principles used in setting standards for these two pollutants may be applied to photochemical pollutants such as ozone which may effect the lung. It is only when the dose-effect relationships between pollution and disease are more clearly understood that the benefit of reducing air pollution to improve health can be predicted.
目前,关于环境空气污染对健康影响的流行病学信息足以设定上限,从而预防慢性肺病患者因污染导致的急性病情恶化。然而,对于什么是安全的慢性背景水平,我们的认识并不完整,尤其是在减少和预防当前发生的慢性呼吸道疾病数量方面。本综述仅专注于二氧化硫和颗粒物污染,尽管为这两种污染物设定标准所采用的原则也可应用于可能影响肺部的光化学污染物,如臭氧。只有当污染与疾病之间的剂量 - 效应关系得到更清晰的理解时,才能预测减少空气污染对改善健康的益处。