Bradwejn J
Psychiatr J Univ Ott. 1989 Jun;14(2):372-4; discussion 379-80.
The author discusses adequate pharmacological treatment for depression. The discussion is based on data from psychopharmacological research, from recommendations given in manuals of psychopharmacology, and from surveys of psychopharmacological practices of affective disorders clinics. The review is limited to the treatment of major depressive episodes with or without melancholia. The treatment of atypical and psychotic depressions is discussed elsewhere. The review is also limited to treatment with non-monoamine oxidase inhibitors antidepressants. The paper is divided in three parts: optimization of treatment; remission rates achieved by optimization of treatment; and lack of optimization of treatment in every day practice and research.
作者探讨了抑郁症的充分药物治疗。该讨论基于精神药理学研究数据、精神药理学手册中的建议以及情感障碍诊所精神药理学实践调查。综述仅限于伴有或不伴有忧郁症的重度抑郁发作的治疗。非典型和精神病性抑郁症的治疗在其他地方讨论。综述还仅限于使用非单胺氧化酶抑制剂抗抑郁药的治疗。本文分为三个部分：治疗优化；通过治疗优化实现的缓解率；以及日常实践和研究中治疗优化的不足。
