Shamsheer R P, Arunachalam Cynthia
Department of Ophthalmology, Yenepoya Medical College, Yenepoya University, Mangalore, Karnataka, India.
Middle East Afr J Ophthalmol. 2015 Oct-Dec;22(4):462-6. doi: 10.4103/0974-9233.167827.
To study the frequency of meibomian gland dysfunction (MGD) in patients of diabetes mellitus with dry eye.
A case-control cross sectional study.
Purposive random sampling. Totally, 200 eyes of 100 patients of diabetes mellitus and an equal number of eyes of normal subjects as control, who were gender and age matched and all of whom were symptomatic for dry eye were assessed for MGD by noting the symptoms and determining the meibomian gland expression scale for volume and viscosity, and ocular surface staining with Lissamine green, and Fluorescein sodium. All the subjects were graded for the severity of MGD. The results were compared in both the groups to ascertain whether the frequency of MGD in diabetics is significantly more as compared to nondiabetics.
The data were analyzed by Chi-square test for significance. P < 0.05 was considered as statistically significant.
There was a significant increase in the frequency of MGD in diabetics as compared to the nondiabetics.
Diabetes mellitus is associated with MGD.
研究糖尿病伴干眼患者睑板腺功能障碍(MGD)的发生率。
一项病例对照横断面研究。
目的抽样。共对100例糖尿病患者的200只眼以及作为对照的同等数量的正常受试者的眼睛进行评估,这些对照与糖尿病患者在性别和年龄上相匹配,且均有干眼症状。通过记录症状、确定睑板腺分泌量和黏度的表达量表,以及用丽丝胺绿和荧光素钠进行眼表染色来评估MGD。所有受试者均按MGD的严重程度分级。比较两组结果以确定糖尿病患者中MGD的发生率是否显著高于非糖尿病患者。
采用卡方检验分析数据的显著性。P < 0.05被认为具有统计学显著性。
与非糖尿病患者相比,糖尿病患者中MGD的发生率显著增加。
糖尿病与MGD有关。