与单克隆丙种球蛋白病相关的弥漫性正常血脂平面性黄瘤。

Cohen Yoon K, Elpern David J

Alta Dermatology, Mesa, AZ, USA.

The Skin Clinic, Williamstown, MA, USA.

Dermatol Pract Concept. 2015 Oct 31;5(4):65-7. doi: 10.5826/dpc.0504a16. eCollection 2015 Oct.

Diffuse normolipemic plane xanthoma (DNPX) was first described by Altman and Winkelmann in 1962. It is a rare and non-inherited form of xanthomatosis. Clinically, the dermatosis is characterized by the presence of symmetric yellowish-orange plaques that favor the neck, upper trunk, flexural folds and periorbital region. It has been recognized to be associated with hematological diseases, especially with multiple myeloma and monoclonal gammopathy. We present a patient with diffuse plane xanthoma, normal lipid level, and monoclonal gammopathy.

弥漫性正常血脂性扁平黄瘤（DNPX）于1962年由阿尔特曼和温克尔曼首次描述。它是一种罕见的、非遗传性的黄瘤病形式。临床上，这种皮肤病的特征是出现对称的黄橙色斑块，好发于颈部、上躯干、屈侧褶皱和眶周区域。它已被认为与血液系统疾病有关，尤其是与多发性骨髓瘤和单克隆丙种球蛋白病有关。我们报告一例患有弥漫性扁平黄瘤、血脂水平正常和单克隆丙种球蛋白病的患者。