Lopez Terry E, Pham Hoang M, Barbour Julia, Tran Phillip, Van Nguyen Benjamin, Hogan Sean P, Homo Richelle L, Coskun Volkan, Schriner Samuel E, Jafari Mahtab
Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, California, USA.
J Funct Foods. 2016 Jan 1;20:556-566. doi: 10.1016/j.jff.2015.11.002.
Although, green tea has numerous health benefits, adverse effects with excessive consumption have been reported. Using , a decrease in male fertility with green tea was evidenced. Here, the extent of green tea toxicity on development and reproduction was investigated. embryos and larvae were exposed to various doses of green tea polyphenols (GTP). Larvae exposed to 10 mg/mL GTP were slower to develop, emerged smaller, and exhibited a dramatic decline in the number of emerged offspring. GTP protected flies against desiccation but sensitized them to starvation and heat stress. Female offspring exhibited a decline in reproductive output and decreased survival while males were unaffected. GTP had a negative impact on reproductive organs in both males and females (e.g., atrophic testes in males, absence of mature eggs in females). Collectively, the data show that high doses of GTP adversely affect development and reproduction of .
尽管绿茶对健康有诸多益处，但也有报道称过量饮用会产生不良影响。研究表明，绿茶会导致雄性生育能力下降。在此，对绿茶对发育和繁殖的毒性程度进行了研究。将胚胎和幼虫暴露于不同剂量的绿茶多酚（GTP）中。暴露于10毫克/毫升GTP的幼虫发育较慢，羽化时体型较小，羽化后代数量急剧下降。GTP保护果蝇免受干燥影响，但使它们对饥饿和热应激敏感。雌性后代的生殖产量下降，存活率降低，而雄性则不受影响。GTP对雄性和雌性的生殖器官都有负面影响（例如，雄性睾丸萎缩，雌性没有成熟卵子）。总体而言，数据表明高剂量的GTP会对[物种名称未明确]的发育和繁殖产生不利影响。
