1 New York Medical College, Valhalla, NY 10905, USA ; 2 Emory University, Atlanta, GA 30322, USA ; 3 American University of Beirut, Beirut, Lebanon ; 4 Saint Joseph University, Beirut, Lebanon ; 5 Morehouse School of Medicine, Atlanta, GA 30310, USA.
Ann Transl Med. 2015 Nov;3(20):321. doi: 10.3978/j.issn.2305-5839.2015.11.28.
We are reporting a case of a patient with a previous history of colorectal cancer (CRC) and cirrhosis, who developed concurrent liver lesions consistent with hepatocellular carcinoma (HCC); a case which is unique due to the low incidence of multiple cancers, particularly HCC in the setting of previous advanced colorectal carcinoma along, in a cirrhotic liver. We will review the known literature on multiple cancer rates found in patients with known colorectal carcinoma. We will then outline this particular patient's presentation, followed by a discussion as to why the particular concurrent development of HCC in the setting of previous CRC is of note.
我们报告了一例既往患有结直肠癌（CRC）和肝硬化的患者，其同时出现符合肝细胞癌（HCC）的肝脏病变；由于先前存在晚期结直肠癌，同时在肝硬化肝脏中，这种情况下同时发生多种癌症（特别是 HCC）的发生率较低，因此该病例较为独特。我们将回顾已知文献中关于已知结直肠癌患者的多种癌症发生率。然后，我们将概述该特定患者的临床表现，接着讨论为什么在先前的 CRC 背景下 HCC 的同时发生值得注意。
