California Department of Toxic Substances Control, California Environmental Protection Agency , 700 Heinz Avenue, Berkeley, California 94710, United States .
VCA Albany Animal Hospital , 1550 Solano Avenue, Albany, California 94707, United States.
Environ Sci Technol. 2016 Feb 2;50(3):1510-8. doi: 10.1021/acs.est.5b04252. Epub 2016 Jan 19.
In this study, we measured serum PBDE levels in California (CA) house cats during two time periods: 2008-2010 and 2012-2013 to assess the impacts of the decline in use of these materials after the bans. The median ∑19PBDE level in CA household cats (age ≥10 yr) was 3479 ng/g lipid in 2008-2010 (1st time period, n = 21) and 1518 ng/g lipid in 2012-2013 (2nd time period, n = 22), about 2 times lower than in the first time period (p = 0.006). In contrast, PCB and OCP levels showed no statistically significant changes. With better matched group size and age (HT = 11 vs non-HT = 11, age ≥10 yr) in the second time period, we found that ∑19PBDE level (mean ± SE ng/g lipid) was significantly higher in the HT group (3906 ± 1442) than those in the non-HT group (1125 ± 244) (p = 0.0030). Higher levels of PCBs and OCPs were also found in HT group. Despite the declines of PBDE levels, our findings indicate that the current levels of PBDEs, as well as PCBs and OCPs, may still pose health effects for house cats and, possibly, humans.
本研究于两个时间段（2008-2010 年和 2012-2013 年）测量了加利福尼亚州（CA）家猫的血清 PBDE 水平，以评估这些物质在禁令后使用减少对其产生的影响。CA 家庭猫（年龄≥10 岁）血清中∑19PBDE 水平的中位数为 2008-2010 年（第 1 个时间段，n=21）3479ng/g 脂质和 2012-2013 年（第 2 个时间段，n=22）1518ng/g 脂质，比第 1 个时间段降低了约 2 倍（p=0.006）。相比之下，PCBs 和 OCPs 水平没有明显变化。在第 2 个时间段，我们发现 HT 组（11 只）与非 HT 组（11 只）的组间大小和年龄（HT=11 岁与非 HT=11 岁，年龄≥10 岁）匹配得更好，∑19PBDE 水平（平均值±SEng/g 脂质）在 HT 组（3906±1442ng/g 脂质）显著高于非 HT 组（1125±244ng/g 脂质）（p=0.0030）。HT 组还发现了更高水平的 PCBs 和 OCPs。尽管 PBDE 水平有所下降，但我们的研究结果表明，目前 PBDEs 以及 PCBs 和 OCPs 的水平可能仍然对家猫甚至人类健康构成影响。
