Puttagunta Harish, Holt Stephen G
Royal Melbourne Hospital, Melbourne, Australia.
Royal Melbourne Hospital, Melbourne, Australia The University of Melbourne, Melbourne, Australia
Perit Dial Int. 2015 Nov;35(6):645-9. doi: 10.3747/pdi.2014.00340.
Heart failure (HF) is a common and important cause of morbidity and mortality in the elderly, imposing a significant burden on healthcare systems. Better management of ischemic heart disease has resulted in increased survival and growth in the number of prevalent heart failure patients, but co-existing renal impairment complicates management and limits traditional therapeutic options. Ultrafiltration (UF) techniques have shown promise in the treatment of diuretic-resistant HF, but the early successes of extracorporeal treatments has not been confirmed by randomized trials. Peritoneal dialysis (PD) may be cheaper and provide more effective UF therapy in selected patients and this review examines the issues surrounding the use of PD for such patients. Whist many nephrologists are enthusiastic about the use of this technique, making a more cogent case for PD in this setting for cardiologists is likely to need a combined strategy of demonstrating improvement in individual cases and further study of potential medicoeconomic benefits.
心力衰竭(HF)是老年人发病和死亡的常见且重要原因,给医疗系统带来了沉重负担。对缺血性心脏病的更好管理已使心力衰竭患者的生存率提高且患病率增加,但并存的肾功能损害使管理变得复杂并限制了传统治疗选择。超滤(UF)技术在治疗利尿剂抵抗性心力衰竭方面显示出前景,但体外治疗的早期成功尚未得到随机试验的证实。腹膜透析(PD)可能成本更低,并且在特定患者中可提供更有效的超滤治疗,本综述探讨了围绕此类患者使用PD的相关问题。尽管许多肾病学家热衷于使用该技术,但要在这种情况下为心脏病学家更有说服力地论证PD的使用,可能需要一种综合策略,即展示个别病例的改善情况以及对潜在医疗经济效益的进一步研究。