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将皮肤癌电子近距离放射治疗纳入社区皮肤科实践。

Incorporation of Electronic Brachytherapy for Skin Cancer into a Community Dermatology Practice.

作者信息

Doggett Stephen, Willoughby Mark, Willoughby Cole, Mafong Erick, Han Amy

机构信息

Aegis Oncology, Tustin, California.

Dermatology and Laser Center, San Diego, California.

出版信息

J Clin Aesthet Dermatol. 2015 Nov;8(11):28-32.

Abstract

OBJECTIVE

The introduction of an electronic brachytherapy delivery system into an existing general dermatology practice is described. Radiobiologic rational for the dose fractionation schedule is detailed.

DESIGN

A miniaturized 50keV x-ray tube and delivery system are United States Food and Drug Administration cleared for nonmelanoma skin cancer. The device is introduced into an existing multi-physician dermatology practice in a standard unshielded treatment room.

SETTING

A multi-site, multi-physician dermatology practice Results: Fifteen months following introduction of the system, a total of 524 nonmelanoma skin cancer patients have been treated. At 12.5 months follow-up, there have been four recurrences and cosmesis has been excellent.

CONCLUSIONS

Advances in radiobiology and radiotechnology permit the treatment course to be given in eight fractions over four weeks. Radiation therapy for nonmelanoma skin cancer can now be given in an office setting as an alternative to Mohs surgery for appropriately selected patients. Results are comparable or better than those of surgery. Advances in radiobiology and radiotechnology permit the treatment course to be given in as few as eight fractions over four weeks. Patients are pleased with the convenience of the short course of therapy given in the office.

摘要

目的

描述将一种电子近距离放射治疗输送系统引入现有的普通皮肤科诊所的情况。详细阐述了剂量分割方案的放射生物学原理。

设计

一种小型化的50keV X射线管和输送系统已获得美国食品药品监督管理局批准用于非黑色素瘤皮肤癌。该设备被引入到一个标准的无屏蔽治疗室中的现有多位医生的皮肤科诊所。

地点

一个多地点、多位医生的皮肤科诊所

结果

系统引入15个月后,共治疗了524例非黑色素瘤皮肤癌患者。在12.5个月的随访中,有4例复发,美容效果极佳。

结论

放射生物学和放射技术的进步使得治疗疗程可以在四周内分八次进行。对于适当选择的患者,现在可以在诊所环境中进行非黑色素瘤皮肤癌的放射治疗,作为莫氏手术的替代方法。结果与手术相当或更好。放射生物学和放射技术的进步使得治疗疗程可以在四周内少至分八次进行。患者对在诊所进行的短疗程治疗的便利性感到满意。

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