Benkert O, Maier W
Department of Psychiatry, University of Mainz, Federal Republic of Germany.
Eur Arch Psychiatry Neurol Sci. 1989;238(5-6):280-4. doi: 10.1007/BF00449809.
Four areas of common interest for clinical psychopharmacology and psychopathology are identified: (1) the diagnostic-based approach in clinical psychopharmacology; (2) the characterization of psychotropic drugs according the main psychopathologically defined target symptoms; (3) prediction of treatment response; (4) development of rating scales. The current state of research strategies in these areas is discussed and the need for new strategies is stressed. In particular, diagnosis-based research strategies in clinical psychopharmacology are not fully justified by empirical data; an alternative approach is discussed.
(1)临床精神药理学中基于诊断的方法;(2)根据主要精神病理学定义的靶症状对精神药物进行特征描述;(3)治疗反应的预测;(4)评定量表的开发。讨论了这些领域研究策略的现状,并强调了新策略的必要性。特别是,临床精神药理学中基于诊断的研究策略并未得到经验数据的充分证明;讨论了另一种方法。