Hunt C M, Harvey J A, Youngs E R, Irwin S T, Reid T M
Department of Histopathology, County Hospital, Lincoln.
J Clin Pathol. 1989 Aug;42(8):847-52. doi: 10.1136/jcp.42.8.847.
The clinical and pathological features of five sporadic cases of enteric infection caused by Escherichia coli O157 (enterohaemorrhagic or Vero cytotoxin-producing E coli showed a range of features. These included one case with pseudomembranous colitis, one with an acute exacerbation of ulcerative colitis, and three with enterocolitis. Diagnostic difficulties encountered initially in four of the five cases were finally resolved by correlating the results of microbiological with histopathological investigations. In view of the heterogeneity of clinical and histological signs and symptoms, it is concluded that all patients with abdominal pain and diarrhoea or rectal bleeding should have early microbiological investigation.
5例由大肠杆菌O157引起的散发性肠道感染（肠出血性或产志贺毒素大肠杆菌）的临床和病理特征呈现出一系列特点。其中包括1例伪膜性结肠炎、1例溃疡性结肠炎急性加重，以及3例小肠结肠炎。5例中有4例最初遇到诊断困难，最终通过将微生物学结果与组织病理学检查结果相关联得以解决。鉴于临床和组织学体征及症状的异质性，得出结论：所有腹痛、腹泻或直肠出血患者均应尽早进行微生物学检查。
