大肠埃希菌O157感染的流行病学：一项为期3年的前瞻性研究。
Epidemiology of infection due to Escherichia coli O157: a 3-year prospective study.
作者信息
MacDonald I A, Gould I M, Curnow J
机构信息
Royal Aberdeen Children's Hospital.
出版信息
Epidemiol Infect. 1996 Jun;116(3):279-84. doi: 10.1017/s0950268800052584.
Abstract
A 3-year study of Escherichia coli infections in Grampian Region was conducted to ascertain the incidence, document clinical sequelae and identify at-risk groups. Approximately 30,000 stools from patients with acute diarrhoea were screened for E. coli O157, and an epidemiological questionnaire filled in for each patient whose stool was positive. Eighty-three patients were studied. The annual incidence was 6 per 100, 000. Proportionately more infections occurred in people involved in agriculture. Evidence was seen of case-to-case transmission, and contamination of a water supply. Eight cases developed haemolytic uraemic syndrome (HUS). There were 2 deaths due to HUS and 2 due to haemorrhagic colitis (HC). Symptomatic E. coli infection is relatively common in the Grampian Region, more common in the agricultural community, and is the main cause of HUS in this Region.
摘要
在格兰扁地区开展了一项为期3年的大肠杆菌感染研究，以确定发病率、记录临床后遗症并识别高危人群。对约30000例急性腹泻患者的粪便进行了大肠杆菌O157筛查，并为每例粪便检测呈阳性的患者填写了一份流行病学调查问卷。对83例患者进行了研究。年发病率为十万分之六。从事农业的人群中感染比例相对较高。发现了病例间传播及水源污染的证据。8例患者发展为溶血尿毒综合征（HUS）。有2例死于HUS，2例死于出血性结肠炎（HC）。有症状的大肠杆菌感染在格兰扁地区相对常见，在农业社区更为常见，并且是该地区HUS的主要病因。
相似文献
1
Epidemiology of infection due to Escherichia coli O157: a 3-year prospective study.大肠埃希菌O157感染的流行病学：一项为期3年的前瞻性研究。
Epidemiol Infect. 1996 Jun;116(3):279-84. doi: 10.1017/s0950268800052584.
2
A severe outbreak of haemorrhagic colitis and haemolytic uraemic syndrome associated with Escherichia coli O157:H7 in Japan.日本发生的与大肠杆菌O157:H7相关的严重出血性结肠炎和溶血尿毒综合征疫情。
Eur J Pediatr. 1994 Sep;153(9):650-5. doi: 10.1007/BF02190685.
3
Haemolytic uraemic syndrome and Shiga toxin-producing Escherichia coli infection in children in France. The Société de Néphrologie Pédiatrique.法国儿童溶血性尿毒症综合征与产志贺毒素大肠杆菌感染。法国儿科肾脏病学会。
Epidemiol Infect. 2000 Apr;124(2):215-20. doi: 10.1017/s0950268899003623.
4
Seasonality and other epidemiological features of haemolytic uraemic syndrome and E. coli O157 isolates in Scotland.
Scott Med J. 1997 Dec;42(6):166-71. doi: 10.1177/003693309704200603.
5
Monitoring patients in the community with suspected Escherichia coli O157 infection during a large outbreak in Scotland in 1996.1996年苏格兰大规模疫情期间对社区疑似感染大肠杆菌O157的患者进行监测。
Epidemiol Infect. 2001 Dec;127(3):413-20. doi: 10.1017/s0950268801006136.
6
7
Clinical course and the role of shiga toxin-producing Escherichia coli infection in the hemolytic-uremic syndrome in pediatric patients, 1997-2000, in Germany and Austria: a prospective study.1997 - 2000年德国和奥地利儿童溶血尿毒综合征中产生志贺毒素大肠杆菌感染的临床病程及作用：一项前瞻性研究
J Infect Dis. 2002 Aug 15;186(4):493-500. doi: 10.1086/341940. Epub 2002 Aug 2.
8
Relative nephroprotection during Escherichia coli O157:H7 infections: association with intravenous volume expansion.大肠杆菌O157:H7感染期间的相对肾脏保护作用：与静脉补液扩容的关系
Pediatrics. 2005 Jun;115(6):e673-80. doi: 10.1542/peds.2004-2236.
9
Desperately seeking diarrhoea: outbreak of haemolytic uraemic syndrome caused by emerging sorbitol-fermenting shiga toxin-producing Escherichia coli O157:H-, Germany, 2009.拼命寻找腹泻：2009 年德国由新兴山梨醇发酵产志贺毒素大肠杆菌 O157:H-引起的溶血性尿毒综合征爆发。
Zoonoses Public Health. 2011 Dec;58(8):567-72. doi: 10.1111/j.1863-2378.2011.01405.x. Epub 2011 Apr 6.
10
A prospective study of exposure to verotoxin-producing Escherichia coli among Canadian children with haemolytic uraemic syndrome. The CPKDRC co-investigators.对加拿大溶血尿毒综合征患儿中接触产志贺毒素大肠杆菌情况的前瞻性研究。加拿大儿科肾脏疾病研究组联合调查人员。
Epidemiol Infect. 1993 Feb;110(1):1-7. doi: 10.1017/s0950268800050615.
引用本文的文献
1
Dietary Indole-3-Carbinol Alleviated Spleen Enlargement, Enhanced IgG Response in C3H/HeN Mice Infected with .饮食吲哚-3-甲醇可缓解 C3H/HeN 感染小鼠的脾肿大，增强 IgG 应答。
Nutrients. 2020 Oct 15;12(10):3148. doi: 10.3390/nu12103148.
2
Tissue Responses to Shiga Toxin in Human Intestinal Organoids.人类肠道类器官中志贺毒素的组织反应。
Cell Mol Gastroenterol Hepatol. 2020;10(1):171-190. doi: 10.1016/j.jcmgh.2020.02.006. Epub 2020 Mar 5.
3
Estimating the burden of foodborne diseases in Japan.估算日本食源性疾病的负担。
Bull World Health Organ. 2015 Aug 1;93(8):540-549C. doi: 10.2471/BLT.14.148056. Epub 2015 Jun 1.
4
Glycolipid binding preferences of Shiga toxin variants.志贺毒素变体的糖脂结合偏好
PLoS One. 2014 Jul 1;9(7):e101173. doi: 10.1371/journal.pone.0101173. eCollection 2014.
5
Management of hemolytic-uremic syndrome in children.儿童溶血尿毒综合征的管理
Int J Nephrol Renovasc Dis. 2014 Jun 12;7:231-9. doi: 10.2147/IJNRD.S41837. eCollection 2014.
6
Chronic sequelae of E. coli O157: systematic review and meta-analysis of the proportion of E. coli O157 cases that develop chronic sequelae.大肠杆菌O157的慢性后遗症：对发生慢性后遗症的大肠杆菌O157病例比例的系统评价和荟萃分析。
Foodborne Pathog Dis. 2014 Feb;11(2):79-95. doi: 10.1089/fpd.2013.1572. Epub 2013 Nov 27.
本文引用的文献
1
Evidence of direct transmission of Escherichia coli O157:H7 infection between calves and a human.大肠杆菌O157:H7在犊牛与人类之间直接传播感染的证据。
J Infect Dis. 1993 Sep;168(3):792-3. doi: 10.1093/infdis/168.3.792.
2
Bacterial typing systems: the way ahead.细菌分型系统：未来之路。
J Med Microbiol. 1994 Jan;40(1):1-2. doi: 10.1099/00222615-40-1-1.
3
Cattle as a possible source of verocytotoxin-producing Escherichia coli O157 infections in man.牛作为人类中产生志贺毒素的大肠杆菌O157感染的可能来源。
Epidemiol Infect. 1993 Dec;111(3):439-47. doi: 10.1017/s0950268800057162.
4
Sporadic cases of haemolytic-uraemic syndrome associated with faecal cytotoxin and cytotoxin-producing Escherichia coli in stools.散发性溶血尿毒综合征病例，与粪便中的细胞毒素及产细胞毒素大肠杆菌有关。
Lancet. 1983 Mar 19;1(8325):619-20. doi: 10.1016/s0140-6736(83)91795-6.
5
The association between idiopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli.特发性溶血尿毒综合征与产志贺毒素大肠杆菌感染之间的关联。
J Infect Dis. 1985 May;151(5):775-82. doi: 10.1093/infdis/151.5.775.
6
Escherichia coli O157:H7 diarrhea in a nursing home: clinical, epidemiological, and pathological findings.养老院中的大肠杆菌O157:H7腹泻：临床、流行病学及病理发现
J Infect Dis. 1986 Oct;154(4):631-8. doi: 10.1093/infdis/154.4.631.
7
A severe outbreak of Escherichia coli O157:H7--associated hemorrhagic colitis in a nursing home.一家养老院中发生的与大肠杆菌O157:H7相关的严重出血性结肠炎疫情。
N Engl J Med. 1987 Dec 10;317(24):1496-500. doi: 10.1056/NEJM198712103172403.
8
Vero cytotoxin-producing strains of Escherichia coli.产志贺毒素大肠杆菌菌株
J Med Microbiol. 1988 Jun;26(2):77-85. doi: 10.1099/00222615-26-2-77.
9
Epidemiology of sporadic diarrhea due to verocytotoxin-producing Escherichia coli: a two-year prospective study.产志贺毒素大肠杆菌所致散发性腹泻的流行病学：一项为期两年的前瞻性研究。
J Infect Dis. 1988 May;157(5):1054-7. doi: 10.1093/infdis/157.5.1054.
10
Vero cytotoxin-producing strains of Escherichia coli from children with haemolytic uraemic syndrome and their detection by specific DNA probes.溶血尿毒综合征患儿中产生维罗毒素的大肠杆菌菌株及其用特异性DNA探针进行的检测
J Med Microbiol. 1988 Apr;25(4):237-43. doi: 10.1099/00222615-25-4-237.
Zotero 插件