Penicillamine-induced bullous pemphigoid with pemphigus-like antibodies.
作者信息
Rasmussen H B, Jepsen L V, Brandrup F
机构信息
Department of Dermatology, Odense University Hospital, Denmark.
出版信息
J Cutan Pathol. 1989 Jun;16(3):154-7. doi: 10.1111/j.1600-0560.1989.tb00031.x.
Abstract
A rheumatoid arthritis case is described who developed bullous skin eruption with mucosal involvement after 3 years of treatment with penicillamine. Histologically, changes compatible with bullous pemphigoid were found. Direct immunofluorescence showed linear, as well as intercellular, deposits of IgG. By indirect immunofluorescence IgG antibodies reacting with the basal membrane zone, as well as the intercellular substance, were detected in the serum. We believe that the patient had bullous pemphigoid with pemphigus-like antibodies induced by penicillamine.
摘要
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Penicillamine-induced bullous pemphigoid with pemphigus-like antibodies.
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