催眠以提高经食管超声心动图耐受性：I-SLEPT研究

HypnosIS to faciLitate trans-Esophageal echocardiograPhy Tolerance: The I-SLEPT study.

作者信息

Corman Isabelle, Bouchema Yasmina, Miquel Béatrice, Rousseau Hélène, Bouvier Dominique, Voilmy Nicolas, Beauvais Florence, Cohen-Solal Alain, Vicaut Eric, Logeart Damien, Tournoux François

机构信息

Service de Cardiologie, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, Université Paris 7, 75010 Paris, France.

Unité de Recherche Clinique, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, Université Paris 7, 75010 Paris, France.

出版信息

Arch Cardiovasc Dis. 2016 Mar;109(3):171-7. doi: 10.1016/j.acvd.2015.09.008. Epub 2015 Dec 23.

DOI:10.1016/j.acvd.2015.09.008

PMID:26711545

Abstract

BACKGROUND

Trans-oesophageal echocardiography (TOE) is one of the major diagnostic tests in cardiovascular medicine, but the procedure is associated with some discomfort for the patient.

AIM

To determine the additive value of hypnosis as a means of improving patient comfort during TOE.

METHODS

We randomly assigned 98 patients with non-emergency indications for TOE to a 30-minute hypnosis session combined with topical oropharyngeal anaesthesia (HYP group) or topical oropharyngeal anaesthesia only (CTRL group) before the procedure. The primary efficacy endpoint was the level of patient discomfort assessed using a visual analogue scale (VAS).

RESULTS

The VAS score was significantly reduced in the HYP group compared with the CTRL group (6 [5; 8] vs. 7 [5; 9]; P=0.046). No statistically significant differences were observed in terms of procedure failure (HYP group 2.2% vs. CTRL group 3.9%; P=1.00) and procedure length (HYP group 7 [5; 11] minutes vs. CTRL group 8 [7; 11] minutes; P=0.29). However, the patients' subjective estimations of the length of the procedure were significantly shorter in the HYP group than in the CTRL group (8 [5; 10] vs. 10 [10; 20] minutes; P<0.0001). There were no major adverse events in either group. The reported minor events rate was lower in the HYP group (36% vs. 57%; P=0.04).

CONCLUSION

Hypnosis is an efficient alternative or complementary method for improving patient comfort during TOE.

摘要

背景

经食管超声心动图（TOE）是心血管医学中的主要诊断检查方法之一，但该检查过程会给患者带来一些不适。

目的

确定催眠作为一种改善经食管超声心动图检查期间患者舒适度的方法的附加价值。

方法

我们将98例有非紧急经食管超声心动图检查指征的患者在检查前随机分为两组，一组接受30分钟的催眠治疗并联合局部口咽麻醉（催眠组），另一组仅接受局部口咽麻醉（对照组）。主要疗效终点是使用视觉模拟量表（VAS）评估的患者不适程度。

结果

与对照组相比，催眠组的VAS评分显著降低（6[5；8]vs.7[5；9]；P=0.046）。在检查失败率（催眠组2.2%vs.对照组3.9%；P=1.00）和检查时长（催眠组7[5；11]分钟vs.对照组8[7；11]分钟；P=0.29）方面未观察到统计学显著差异。然而，催眠组患者对检查时长的主观估计明显短于对照组（8[5；10]vs.10[10；20]分钟；P<0.0001）。两组均未发生重大不良事件。催眠组报告的轻微事件发生率较低（36%vs.57%；P=0.04）。