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饮食对麻风分枝杆菌在小鼠足垫中生长的影响。

Effect of diet on growth of M. leprae in mouse footpads.

作者信息

Foster R L, Sanchez A, Small C, Lau B H, Stuyvesant W, Foster F N, Baldwin B E

机构信息

B.S. Leprosy Research Foundation, Loma Linda, California.

出版信息

Indian J Lepr. 1989 Jul;61(3):360-6.

PMID:2671180
Abstract

Semipurified diets, with equal amounts of vitamins, minerals and fibre, but varied in protein and fat content from pork, barbel fish or soya beans were tested for their possible effect on the growth of M. leprae in mouse footpads. 105 BALB/c male weanling mice were randomly divided into five diet groups of 21 mice each and fed for six months. Differences between bacterial counts of diet groups were found. The mouse foot pad model is suitable for dietary study in leprosy.

摘要

对含有等量维生素、矿物质和纤维,但蛋白质和脂肪含量因猪肉、鲇鱼或大豆而异的半纯化饮食进行了测试,以研究其对小鼠足垫中麻风杆菌生长的可能影响。105只BALB/c雄性断奶小鼠被随机分为五个饮食组,每组21只,喂养六个月。发现饮食组之间的细菌计数存在差异。小鼠足垫模型适用于麻风病的饮食研究。

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