Vecchio R, Intagliata E, Fiumara P F, Villari L, Marchese S, Cacciola E
G Chir. 2015 Sep-Oct;36(5):222-4. doi: 10.11138/gchir/2015.36.5.222.
Myeloid sarcoma is a tumor composed of myeloblasts occurring at an extramedullary site. It may develop in patients with acute myeloid leukemia, myeloproliferative or myelodysplastic syndrome, sometimes preceding onset of the systemic disease. Frequent sites of myeloid sarcoma are bones or various soft tissues. Gastrointestinal involvement is very rare. We report a unique case of myeloid sarcoma presenting as a painful anal fissure, in a patient with a history of acute myeloid leukemia. The diagnosis was achieved by a surgical excisional biopsy and immunoistochemical staining.
髓系肉瘤是一种由髓母细胞组成的肿瘤，发生于髓外部位。它可能在急性髓系白血病、骨髓增殖性或骨髓增生异常综合征患者中发生，有时在全身性疾病发病之前出现。髓系肉瘤常见部位是骨骼或各种软组织。胃肠道受累非常罕见。我们报告一例独特的髓系肉瘤病例，表现为疼痛性肛裂，患者有急性髓系白血病病史。通过手术切除活检和免疫组织化学染色得以确诊。
