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表现为急性胰腺炎症状且酷似胰腺癌的髓外髓样肉瘤

Extramedullary Myeloid Sarcoma with Symptoms of Acute Pancreatitis Mimicking Pancreatic Carcinoma.

作者信息

Clausen Sean, Oberoi Mansi, Lynch Douglas, Maher George, Ridgway Timothy, Atiq Muslim

机构信息

Division of Gastroenterology and Hepatology, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.

Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.

出版信息

S D Med. 2020 Jul;73(7):305-307.

PMID:32805779
Abstract

Extramedullary myeloid sarcomas are extramedullary tumors of immature myeloid cells, often associated with acute myeloid leukemia (AML), chronic myeloid leukemia (CML), or other myeloproliferative diseases. They are usually found in connective/soft tissues, skin, breast and gastrointestinal system. Pancreas is an uncommon site to be involved. We present a case of pancreatic myeloid sarcoma presenting with symptoms of acute pancreatitis including epigastric pain associated with nausea and vomiting, with imaging findings (abdominal CT) suggestive of pancreatic carcinoma, both presenting as hypoattenuating mass. It is important to consider myeloid sarcoma as a differential for pancreatic mass, especially given the history of AML as in our patient, which would lead to timely diagnosis and initiation of chemotherapy.

摘要

髓外髓样肉瘤是未成熟髓样细胞的髓外肿瘤,常与急性髓系白血病(AML)、慢性髓系白血病(CML)或其他骨髓增殖性疾病相关。它们通常见于结缔组织/软组织、皮肤、乳腺和胃肠道系统。胰腺是较少受累的部位。我们报告一例胰腺髓样肉瘤病例,该病例表现为急性胰腺炎症状,包括上腹部疼痛伴恶心和呕吐,影像学检查(腹部CT)提示胰腺癌,两者均表现为低密度肿块。将髓样肉瘤作为胰腺肿块的鉴别诊断很重要,特别是像我们的患者有AML病史的情况下,这将有助于及时诊断并开始化疗。

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