皮肤出血性病变广泛手术切除的意外组织病理学结果：一例腿部默克尔细胞癌
Unexpected histopathologic result of a wide surgical excision of a bleeding lesion of the skin: a case of Merkel cell carcinoma of the leg.
作者信息
Cestaro G, Festa P, Cricrì A M, Antropoli M, Castriconi M
出版信息
G Chir. 2015 Sep-Oct;36(5):231-5. doi: 10.11138/gchir/2015.36.5.231.
BACKGROUND
Merkel cell Carcinoma is a very rare primary cutaneous tumor that often looks like an innocuous and asymptomatic nodule or plaque of the skin, but with a very fast growing. It is also called neuroendocrine carcinoma of the skin or trabecular cancer. The main treatment is based on a local excision followed by radiotherapy or chemotherapy. The most common site of presentation of this lesion is head and neck (40-60%.) and it often occur in older men with immunological system dysfunction like HIV patients, cancer, severe infections and immunosuppression for transplantation.
METHODS
The authors report a case of a bleeding Merkel Cell Carcinoma of the right leg in a 83 years old man with HCV infection, chronic kidney disease and diabetes mellitus type 2 that required local excision.
RESULTS
Lesion was entirely removed and then patient was sent to oncologists. After two months from surgical excision, healing process is regular and without complications.
CONCLUSIONS
This type of tumor can be misdiagnosed and, if bleeding, it can represent a serious surgical emergency.
背景
默克尔细胞癌是一种非常罕见的原发性皮肤肿瘤，通常表现为皮肤表面无害且无症状的结节或斑块，但生长速度极快。它也被称为皮肤神经内分泌癌或小梁癌。主要治疗方法是局部切除，随后进行放疗或化疗。该病变最常见的发病部位是头颈部（40 - 60%），且常发生于免疫系统功能障碍的老年男性，如艾滋病患者、癌症患者、严重感染者以及因移植而免疫抑制的人群。
方法
作者报告了一例83岁男性右下肢出血性默克尔细胞癌病例，该患者患有丙型肝炎病毒感染、慢性肾病和2型糖尿病，需要进行局部切除。
结果
病变被完全切除，随后患者被转至肿瘤学家处。手术切除两个月后，愈合过程正常，无并发症。
结论
这种类型的肿瘤可能会被误诊，若出现出血情况，则可能代表严重的外科急症。
Zotero 插件