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将颈动脉内膜切除术与非体外循环冠状动脉旁路移植术相结合是安全有效的。

Combining carotid endarterectomy with off-pump coronary artery bypass graft surgery is safe and effective.

作者信息

Garg Arun, Bansal Atma Ram, Singh Dilip, Mishra Manisha, Sharma Pooja, Kasliwal Ravi Ratan, Trehan Naresh

机构信息

Institute of Neuroscience, Medanta The Medicity, Gurgaon, Haryana, India.

Institute of Critical Care and Anesthesia, Medanta The Medicity, Gurgaon, Haryana, India.

出版信息

Ann Indian Acad Neurol. 2015 Oct-Dec;18(4):419-23. doi: 10.4103/0972-2327.165457.

DOI:10.4103/0972-2327.165457
PMID:26713014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4683881/
Abstract

BACKGROUND

We, as neurologists, are frequently consulted to give neurological clearance for surgery in patients who are undergoing coronary artery bypass graft (CABG) surgery and have suffered from stroke or transient ischemic attack (TIA) in past. Similarly clearance is also sought in another group of patients who, though have not suffered from stroke or TIA, but found to have significant carotid stenosis on routine screening prior to surgery. Cardiac surgeons and anesthetists want to know the risk of perioperative stroke in such patients and should carotid endarterectomy (CEA) be done along with CABG. In absence of any clear-cut guideline, neurologists often fail to give any specific recommendation.

AIM

To find out safety and efficacy of synchronous CEA in patients undergoing CABG.

DESIGN

Retrospective study.

MATERIALS AND METHODS

Out of 3,700 patients who underwent CABG, 150 were found to have severe carotid stenosis of >70%. Out of this, 46 patients with >80% stenosis (three symptomatic and 43 asymptomatic) and one patient with >70% symptomatic carotid stenosis (TIA within last 2 weeks) were taken for simultaneous CEA along with CABG. These three symptomatic carotid patients had suffered from stroke within last 6 months.

RESULTS

One patient with asymptomatic near total occlusion of carotid artery suffered from hyperperfusion syndrome. None suffered from ischemic stroke, myocardial infarction (MI), or death during perioperative period.

CONCLUSION

Combining CEA along with CABG is a safe and effective procedure.

摘要

背景

作为神经科医生,我们经常被咨询,为正在接受冠状动脉搭桥术(CABG)且既往有中风或短暂性脑缺血发作(TIA)的患者进行手术的神经学评估。同样,另一组患者也会寻求评估,这些患者虽然没有中风或TIA病史,但在手术前的常规筛查中发现有严重的颈动脉狭窄。心脏外科医生和麻醉师想了解这类患者围手术期中风的风险,以及是否应在CABG的同时进行颈动脉内膜切除术(CEA)。由于缺乏明确的指导方针,神经科医生往往无法给出具体建议。

目的

了解同步进行CEA对接受CABG患者的安全性和有效性。

设计

回顾性研究。

材料与方法

在3700例接受CABG的患者中,发现150例有严重颈动脉狭窄,狭窄程度>70%。其中,46例狭窄程度>80%的患者(3例有症状,43例无症状)和1例狭窄程度>70%的有症状颈动脉狭窄患者(在过去2周内发生TIA)在进行CABG的同时接受了同步CEA。这3例有症状的颈动脉患者在过去6个月内曾发生中风。

结果

1例无症状的颈动脉近乎完全闭塞的患者发生了高灌注综合征。围手术期无患者发生缺血性中风、心肌梗死(MI)或死亡。

结论

CEA与CABG联合是一种安全有效的手术方法。

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本文引用的文献

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2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery. Developed in collaboration with the American Academy of Neurology and Society of Cardiovascular Computed Tomography.2011年美国麻醉医师协会/美国心脏病学会基金会/美国心脏协会/美国神经学会护士协会/美国神经外科医师协会/美国放射学会/美国神经放射学会/神经外科医师大会/动脉粥样硬化影像与预防学会/心血管造影和介入学会/介入放射学会/神经介入外科学会/血管医学学会和血管外科学会关于颅外颈动脉和椎动脉疾病患者管理的指南:执行摘要:美国心脏病学会基金会/美国心脏协会实践指南工作组、美国中风协会、美国神经科学护士协会、美国神经外科医师协会、美国放射学会、美国神经放射学会、神经外科医师大会、动脉粥样硬化影像与预防学会、心血管造影和介入学会、介入放射学会、神经介入外科学会、血管医学学会和血管外科学会的报告。与美国神经病学学会和心血管计算机断层扫描学会合作制定。
Catheter Cardiovasc Interv. 2013 Jan 1;81(1):E76-123. doi: 10.1002/ccd.22983. Epub 2011 Feb 3.
5
The role of combined carotid endarterectomy and coronary artery bypass grafting in the era of carotid stenting in view of long-term results.鉴于长期结果,探讨在颈动脉支架置入时代联合颈动脉内膜切除术和冠状动脉旁路移植术的作用。
Interact Cardiovasc Thorac Surg. 2012 Dec;15(6):984-8. doi: 10.1093/icvts/ivs398. Epub 2012 Sep 11.
6
Carotid artery stenting and cardiac surgery in symptomatic patients.症状性患者颈动脉支架置入术与心脏手术。
JACC Cardiovasc Interv. 2011 Nov;4(11):1190-6. doi: 10.1016/j.jcin.2011.07.012.
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Patients with severe asymptomatic carotid artery stenosis do not have a higher risk of stroke and mortality after coronary artery bypass surgery.无症状性严重颈动脉狭窄患者行冠状动脉旁路手术后卒中与死亡风险并未升高。
Stroke. 2011 Oct;42(10):2801-5. doi: 10.1161/STROKEAHA.111.618082. Epub 2011 Aug 4.
8
Short-term results of a randomized trial examining timing of carotid endarterectomy in patients with severe asymptomatic unilateral carotid stenosis undergoing coronary artery bypass grafting.一项随机临床试验的短期结果,该试验研究了在接受冠状动脉旁路移植术的严重无症状单侧颈动脉狭窄患者中颈动脉内膜切除术的时机。
J Vasc Surg. 2011 Oct;54(4):993-9; discussion 998-9. doi: 10.1016/j.jvs.2011.03.284. Epub 2011 Jun 23.
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Stroke after cardiac surgery and its association with asymptomatic carotid disease: an updated systematic review and meta-analysis.心脏手术后的中风及其与无症状颈动脉疾病的关系:一项更新的系统评价和荟萃分析。
Eur J Vasc Endovasc Surg. 2011 May;41(5):607-24. doi: 10.1016/j.ejvs.2011.02.016. Epub 2011 Mar 10.
10
Part Two: Against the motion. Carotid disease is responsible for the increased risk of stroke after coronary bypass surgery.第二部分:反对该观点。颈动脉疾病是冠状动脉搭桥手术后中风风险增加的原因。
Eur J Vasc Endovasc Surg. 2010 Dec;40(6):693-5. doi: 10.1016/j.ejvs.2010.09.004.