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皮肤病中的血脂异常。

Dyslipidemia in Dermatological Disorders.

作者信息

Shenoy Chetana, Shenoy Manjunath Mala, Rao Gururaja K

机构信息

Department of Dermatology, Yenepoya Medical College, Yenepoya University, Deralakatte, Mangalore, Karnataka, India.

Department of Endocrinolgy, Yenepoya Medical College, Yenepoya University, Deralakatte, Mangalore, Karnataka, India.

出版信息

N Am J Med Sci. 2015 Oct;7(10):421-8. doi: 10.4103/1947-2714.168657.

Abstract

Dyslipidemias are one of the common metabolic disorders. A link between dermatological disorders like psoriasis and dyslipidemia has been established in the recent past. Many dermatological disorders could have a systemic inflammatory component which explains such association. Chronic inflammatory dermatological disorders could also have other metabolic imbalances that may contribute to dyslipidemia. Presence of such abnormal metabolism may justify routine screening of these disorders for associated dyslipidemia and other metabolic abnormalities and early treatment of such comorbidities to improve quality of life. Some of the drugs used by dermatologists such as retinoids are also likely to be a cause of dyslipidemia. Hence, it is imperative that the dermatologists obtain scientific knowledge on the underlying mechanisms involved in dyslipidemia and understand when to intervene with therapies. A systematic review of the English language literature was done by using Google Scholar and PubMed. In this review, attempts are made to list the dermatological disorders associated with dyslipidemia; to simplify the understanding of underlying mechanisms; and to give a brief idea about the interventions.

摘要

血脂异常是常见的代谢紊乱之一。银屑病等皮肤病与血脂异常之间的联系在最近已得到证实。许多皮肤病可能存在全身炎症成分,这就解释了这种关联。慢性炎症性皮肤病也可能存在其他代谢失衡,这可能导致血脂异常。这种异常代谢的存在可能说明对这些疾病进行常规筛查以检测相关血脂异常和其他代谢异常,并对这些合并症进行早期治疗以提高生活质量是合理的。皮肤科医生使用的一些药物,如维甲酸类药物,也可能是血脂异常的一个原因。因此,皮肤科医生必须掌握有关血脂异常潜在机制的科学知识,并了解何时进行治疗干预。我们通过谷歌学术和PubMed对英文文献进行了系统综述。在本综述中,我们试图列出与血脂异常相关的皮肤病;简化对潜在机制的理解;并简要介绍干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44b2/4677465/d06fb8bfc859/NAJMS-7-421-g002.jpg

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