Padhi Tanmay
Department of Dermatology and Venereology, VSS Medical College, Sambalpur, Odisha, India.
Indian J Dermatol. 2013 Jul;58(4):299-305. doi: 10.4103/0019-5154.113950.
Metabolic syndrome (Met S) is a clustering of risk factors comprising of abdominal obesity, dyslipidemia, elevated blood pressure, and abnormal glucose tolerance. The prevalence of Met S has been increasing in the last few years throughout the world. Psoriasis has consistently been associated with Met S as well as its various components. However, the association is no longer limited to psoriasis alone. Various dermatological conditions such as lichen planus, androgenetic alopecia, systemic lupus erythematosus, skin tags, acanthosis nigricans, and even cutaneous malignancies have also been found to be associated with this syndrome. Though chronic inflammation is thought to be the bridging link, the role of oxidative stress and endocrine abnormalities has recently been proposed in bringing them together.
代谢综合征（Met S）是一组危险因素的聚集，包括腹部肥胖、血脂异常、血压升高和糖耐量异常。在过去几年中，全球范围内代谢综合征的患病率一直在上升。银屑病一直与代谢综合征及其各个组成部分相关。然而，这种关联不再仅限于银屑病。各种皮肤病，如扁平苔藓、雄激素性脱发、系统性红斑狼疮、皮肤软纤维瘤、黑棘皮病，甚至皮肤恶性肿瘤，也被发现与该综合征有关。尽管慢性炎症被认为是连接两者的桥梁，但最近有人提出氧化应激和内分泌异常在将它们联系起来方面也发挥了作用。
