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[中国成年人膳食胆固醇与血清胆固醇关系的研究]

[Study on the relationships between dietary cholesterol and serum cholesterol among Chinese adults].

作者信息

Su Chang, Jia Xiaofang, Wang Zhihong, Wang Huijun, Zhang Bing

机构信息

National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.

National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China; Email:

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2015 Aug;36(8):842-5.

Abstract

OBJECTIVE

To describe the relationships between dietary cholesterol and serum cholesterol among Chinese adults.

METHODS

Data used in the present study was from the China Health and Nutrition Study (CHNS). Chinese adults, 18 to 65 year olds who participated in the 2009 CHNS with complete individual information were included in the study. Correlation of dietary cholesterol and serum cholesterol among different sex groups was described to explore the effect of dietary cholesterol intake on the level of serum cholesterol as well as to examine the effect of higher intake of dietary cholesterol related to hypercholesterolemia.

RESULTS

Results from the correlation analysis indicated that dietary cholesterol appeared a highly positive correlation (P < 0.05) with serum total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C). Data from the multiple regression analysis showed that dietary cholesterol intake was an important factor that affecting the serum TC (P < 0.05) in both males and females but LDL-C was only in females (P = 0.01). After adjusting for potential confounders, the high intake of dietary cholesterol (≥ 300 mg/d) had higher risks for developing hypercholesterolemia in both males and females (OR = 1.21, 95% CI: 1.03-1.42, P = 0.019; OR = 1.18, 95% CI: 1.00-1.40, P = 0.044), respectively.

CONCLUSION

Dietary cholesterol intake seemed to correlate with the serum cholesterol level, and hypercholesterolemia should be prevented through reducing the dietary cholesterol among Chinese adults.

摘要

目的

描述中国成年人膳食胆固醇与血清胆固醇之间的关系。

方法

本研究使用的数据来自中国健康与营养调查(CHNS)。纳入了参与2009年CHNS且拥有完整个人信息的18至65岁中国成年人。描述不同性别组中膳食胆固醇与血清胆固醇的相关性,以探讨膳食胆固醇摄入量对血清胆固醇水平的影响,并检验与高胆固醇血症相关的较高膳食胆固醇摄入量的影响。

结果

相关性分析结果表明,膳食胆固醇与血清总胆固醇(TC)和低密度脂蛋白胆固醇(LDL-C)呈高度正相关(P<0.05)。多元回归分析数据显示,膳食胆固醇摄入量是影响男性和女性血清TC的重要因素(P<0.05),但仅对女性的LDL-C有影响(P=0.01)。在调整潜在混杂因素后,膳食胆固醇高摄入量(≥300毫克/天)的男性和女性患高胆固醇血症的风险均较高(OR=1.21,95%CI:1.03-1.42,P=0.019;OR=1.18,95%CI:1.00-1.40,P=0.044)。

结论

膳食胆固醇摄入量似乎与血清胆固醇水平相关,应通过减少中国成年人的膳食胆固醇来预防高胆固醇血症。

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