Bastianelli Mark, Kilty Shaun J
Department of Otolaryngology-Head and Neck Surgery, University of Ottawa, The Ottawa Hospital, 737 Parkdale Ave., Room 459, Ottawa, ON, K1Y 1J8, Canada.
Ottawa Hospital Research Institute (OHRI), Ottawa, ON, Canada.
J Otolaryngol Head Neck Surg. 2015 Dec 30;44:59. doi: 10.1186/s40463-015-0112-4.
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease that results in telangiectasia of the sinonasal tract, gastro-intestinal tract as well as possible arteriovenous malformations of the lung, liver and brain. One of the most common disease manifestations of HHT is epistaxis. Severe recurrent epistaxis necessitating iron therapy and blood transfusion is often managed with septodermoplasty. Its initial description was as an open surgical technique requiring nasal packing.
We describe a modified approach to septodermoplasty done completely endoscopically and without nasal packing for a patient with severe epistaxis due to HHT.
The described technique modifications for the presented case allowed for same day discharge following surgery, complete take of the skin graft and resultant epistaxis control that ended thepatient's transfusion dependency. The merits of these modifications should be further evaluated in a clinical trial.
遗传性出血性毛细血管扩张症(HHT)是一种常染色体显性疾病,可导致鼻窦、胃肠道出现毛细血管扩张,以及肺部、肝脏和脑部可能出现动静脉畸形。HHT最常见的疾病表现之一是鼻出血。严重的复发性鼻出血需要进行铁剂治疗和输血,通常采用鼻中隔皮瓣成形术进行处理。其最初的描述是一种需要鼻腔填塞的开放性手术技术。
我们描述了一种针对因HHT导致严重鼻出血的患者,完全在内窥镜下且无需鼻腔填塞的改良鼻中隔皮瓣成形术方法。
所描述的针对该病例的技术改良使得患者术后当天即可出院,植皮完全成活,鼻出血得到控制,从而结束了患者对输血的依赖。这些改良的优点应在临床试验中进一步评估。