Simpson Robin, Devenyi Gabriel A, Jezzard Peter, Hennessy T Jay, Near Jamie
Department of Radiology, Medical Physics, Freiburg University, Freiburg, Germany.
Centre d'Imagerie Cérébrale, Douglas Mental Health University Institute, Montreal, Canada.
Magn Reson Med. 2017 Jan;77(1):23-33. doi: 10.1002/mrm.26091. Epub 2015 Dec 30.
To introduce a new toolkit for simulation and processing of magnetic resonance spectroscopy (MRS) data, and to demonstrate some of its novel features.
The FID appliance (FID-A) is an open-source, MATLAB-based software toolkit for simulation and processing of MRS data. The software is designed specifically for processing data with multiple dimensions (eg, multiple radiofrequency channels, averages, spectral editing dimensions). It is equipped with functions for importing data in the formats of most major MRI vendors (eg, Siemens, Philips, GE, Agilent) and for exporting data into the formats of several common processing software packages (eg, LCModel, jMRUI, Tarquin). This paper introduces the FID-A software toolkit and uses examples to demonstrate its novel features, namely 1) the use of a spectral registration algorithm to carry out useful processing routines automatically, 2) automatic detection and removal of motion-corrupted scans, and 3) the ability to perform several major aspects of the MRS computational workflow from a single piece of software. This latter feature is illustrated through both high-level processing of in vivo GABA-edited MEGA-PRESS MRS data, as well as detailed quantum mechanical simulations to generate an accurate LCModel basis set for analysis of the same data.
All of the described processing steps resulted in a marked improvement in spectral quality compared with unprocessed data. Fitting of MEGA-PRESS data using a customized basis set resulted in improved fitting accuracy compared with a generic MEGA-PRESS basis set.
The FID-A software toolkit enables high-level processing of MRS data and accurate simulation of in vivo MRS experiments. Magn Reson Med 77:23-33, 2017. © 2015 Wiley Periodicals, Inc.
介绍一种用于磁共振波谱（MRS）数据模拟和处理的新工具包，并展示其一些新颖特性。
FID设备（FID-A）是一个基于MATLAB的开源软件工具包，用于MRS数据的模拟和处理。该软件专为处理多维数据（例如，多个射频通道、平均值、频谱编辑维度）而设计。它具备以大多数主要MRI供应商（例如，西门子、飞利浦、通用电气、安捷伦）的格式导入数据以及以几种常见处理软件包（例如，LCModel、jMRUI、Tarquin）的格式导出数据的功能。本文介绍了FID-A软件工具包，并通过示例展示其新颖特性，即1）使用频谱配准算法自动执行有用的处理程序，2）自动检测和去除运动损坏的扫描，以及3）能够从单个软件执行MRS计算工作流程的几个主要方面。通过对体内GABA编辑的MEGA-PRESS MRS数据的高级处理以及生成用于分析相同数据的准确LCModel基集的详细量子力学模拟来说明后一个特性。
与未处理的数据相比，所有描述的处理步骤均导致频谱质量有显著提高。与通用的MEGA-PRESS基集相比，使用定制基集对MEGA-PRESS数据进行拟合可提高拟合精度。
FID-A软件工具包能够对MRS数据进行高级处理，并对体内MRS实验进行准确模拟。《磁共振医学》77:23 - 33, 2017。© 2015威利期刊公司。
