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鼠伤寒沙门氏菌LT2 gnd基因的克隆、核苷酸序列及其与大肠杆菌K12相应序列的同源性

Cloning and nucleotide sequence of the Salmonella typhimurium LT2 gnd gene and its homology with the corresponding sequence of Escherichia coli K12.

作者信息

Reeves P, Stevenson G

机构信息

Department of Microbiology, University of Sydney, Australia.

出版信息

Mol Gen Genet. 1989 May;217(1):182-4. doi: 10.1007/BF00330960.

DOI:10.1007/BF00330960
PMID:2671649
Abstract

The complete nucleotide sequence of the Salmonella strain LT2 gnd gene for 6-phosphogluconate dehydrogenase was determined. The gene contains 1404 bases and encodes a 468 amino acid polypeptide, which is the same as for Escherichia coli K12. The DNA sequence shows 14.8% difference between the two and the amino acid sequence 3.6% difference. Changes are mostly in the third codon base and most of the amino acid changes are conservative.

摘要

测定了鼠伤寒沙门氏菌LT2菌株6-磷酸葡萄糖酸脱氢酶gnd基因的完整核苷酸序列。该基因含有1404个碱基，编码一个468个氨基酸的多肽，这与大肠杆菌K12的相同。DNA序列显示两者之间有14.8%的差异，氨基酸序列有3.6%的差异。变化大多在第三个密码子碱基上，且大多数氨基酸变化是保守的。

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DNA sequence of the Escherichia coli gene, gnd, for 6-phosphogluconate dehydrogenase.大肠杆菌6-磷酸葡萄糖酸脱氢酶基因（gnd）的DNA序列。
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Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes.大肠杆菌转移RNA丰度与其蛋白质基因中相应密码子出现情况之间的相关性。
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