The rs1049353 polymorphism in the CNR1 gene interacts with childhood abuse to predict posttraumatic threat symptoms.
作者信息
Mota Natalie, Sumner Jennifer A, Lowe Sarah R, Neumeister Alexander, Uddin Monica, Aiello Allison E, Wildman Derek E, Galea Sandro, Koenen Karestan C, Pietrzak Robert H
机构信息
US Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven.
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
出版信息
J Clin Psychiatry. 2015 Dec;76(12):e1622-3. doi: 10.4088/JCP.15l10084.
Abstract
摘要
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The rs1049353 polymorphism in the CNR1 gene interacts with childhood abuse to predict posttraumatic threat symptoms.CNR1基因中的rs1049353多态性与童年期虐待相互作用，以预测创伤后威胁症状。
J Clin Psychiatry. 2015 Dec;76(12):e1622-3. doi: 10.4088/JCP.15l10084.
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Elucidating the transdiagnostic dimensional structure of trauma-related psychopathology: Findings from VA cooperative study 504 - risperidone treatment for military service related chronic post traumatic stress disorder.阐明创伤相关精神病理学的跨诊断维度结构：退伍军人事务部合作研究504的结果——利培酮治疗与军事服务相关的慢性创伤后应激障碍
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Assessing the fit of the Dysphoric Arousal model across two nationally representative epidemiological surveys: The Australian NSMHWB and the United States NESARC.评估两个具有全国代表性的流行病学调查（澳大利亚 NSMHWB 和美国 NESARC）中不愉悦唤起模型的拟合度。
J Anxiety Disord. 2013 Jan;27(1):109-15. doi: 10.1016/j.janxdis.2012.10.006. Epub 2012 Nov 17.
7
Cannabinoid receptor genotype moderation of the effects of childhood physical abuse on anhedonia and depression.大麻素受体基因型对童年期身体虐待所致快感缺失和抑郁效应的调节作用
Arch Gen Psychiatry. 2012 Jul;69(7):732-40. doi: 10.1001/archgenpsychiatry.2011.2273.
8
Epigenetic and immune function profiles associated with posttraumatic stress disorder.与创伤后应激障碍相关的表观遗传和免疫功能特征。
Proc Natl Acad Sci U S A. 2010 May 18;107(20):9470-5. doi: 10.1073/pnas.0910794107. Epub 2010 May 3.
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Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder.大麻素受体基因（CNR1）与注意力缺陷多动障碍及创伤后应激障碍的关联。
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