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心脏死亡后肺脏捐赠:捐赠者标准、程序标准、肺移植功能验证及保存

DCD lung donation: donor criteria, procedural criteria, pulmonary graft function validation, and preservation.

作者信息

Erasmus Michiel E, van Raemdonck Dirk, Akhtar Mohammed Zeeshan, Neyrinck Arne, de Antonio David Gomez, Varela Andreas, Dark John

机构信息

Department of Cardiothoracic Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.

出版信息

Transpl Int. 2016 Jul;29(7):790-7. doi: 10.1111/tri.12738. Epub 2016 Jan 15.

Abstract

In an era where there is a shortage of lungs for transplantation is increased utilization of lungs from donation after circulatory death (DCD) donors. We review the reports of 11 controlled and 1 uncontrolled DCD programs focusing on donor criteria, procedural criteria, graft assessment, and preservation techniques including the use of ex vivo lung perfusion. We have formulated conclusions and recommendations for each of these areas, which were presented at the 6th International Conference on Organ Donation. A table of recommendations, the grade of recommendations, and references are provided.

摘要

在一个肺移植供体短缺的时代,循环死亡后捐赠(DCD)供体的肺利用率有所提高。我们回顾了11个对照和1个非对照DCD项目的报告,重点关注供体标准、程序标准、移植物评估和保存技术,包括体外肺灌注的使用。我们针对这些领域中的每一个都制定了结论和建议,并在第6届国际器官捐赠会议上进行了展示。提供了一份建议表、建议等级和参考文献。

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