心脏循环死亡后供体与肺移植
Donors after cardiocirculatory death and lung transplantation.
作者信息
Inci Ilhan
机构信息
Department of Thoracic Surgery, University Hospital, University of Zurich, Zurich, Switzerland.
出版信息
J Thorac Dis. 2017 Aug;9(8):2660-2669. doi: 10.21037/jtd.2017.07.82.
Abstract
The number of patients actively awaiting lung transplantation (LTx) is more than the number of suitable donor lungs. The percentage of lung retrieval rate is lower when compared to other solid organs. The use of lungs from donation after cardiocirculatory death (DCD) donors is one of the options to avoid organ shortage in LTx. After extensive experimental research, clinical application of DCD donation is becoming wider. The results from most of the centers show at least equal survival rate compared to donors from brain death. This review paper will summarize experimental background and clinical experience from DCD donors.
摘要
积极等待肺移植（LTx）的患者数量超过了合适供肺的数量。与其他实体器官相比，肺获取率的百分比更低。使用心源性循环死亡（DCD）供体的肺是避免肺移植中器官短缺的选择之一。经过广泛的实验研究，DCD供体的临床应用正在变得更加广泛。大多数中心的结果显示，与脑死亡供体相比，生存率至少相当。这篇综述文章将总结DCD供体的实验背景和临床经验。
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本文引用的文献
1
Short- and Long-term Outcomes After Lung Transplantation From Circulatory-Dead Donors: A Single-Center Experience.
Transplantation. 2017 Nov;101(11):2691-2694. doi: 10.1097/TP.0000000000001678.
2
Pathophysiological Trends During Withdrawal of Life Support: Implications for Organ Donation After Circulatory Death.
Transplantation. 2016 Dec;100(12):2621-2629. doi: 10.1097/TP.0000000000001396.
3
Steroids can reduce warm ischemic reperfusion injury in a porcine donation after circulatory death model with ex vivo lung perfusion evaluation.
Transpl Int. 2016 Nov;29(11):1237-1246. doi: 10.1111/tri.12823.
4
Attenuation of Pulmonary Ischemia-Reperfusion Injury by Adenosine A2B Receptor Antagonism.
Ann Thorac Surg. 2016 Aug;102(2):385-393. doi: 10.1016/j.athoracsur.2016.02.060. Epub 2016 Apr 22.
5
New classification of donation after circulatory death donors definitions and terminology.
Transpl Int. 2016 Jul;29(7):749-59. doi: 10.1111/tri.12776. Epub 2016 May 4.
6
Lungs From the Controlled Donation After Circulatory Determination of Death Donor: Perspectives From the United States and Beyond.
Am J Transplant. 2016 Apr;16(4):1047-8. doi: 10.1111/ajt.13600. Epub 2016 Feb 4.
7
Lung Quality and Utilization in Controlled Donation After Circulatory Determination of Death Within the United States.
Am J Transplant. 2016 Apr;16(4):1207-15. doi: 10.1111/ajt.13599. Epub 2016 Feb 4.
8
DCD lung donation: donor criteria, procedural criteria, pulmonary graft function validation, and preservation.
Transpl Int. 2016 Jul;29(7):790-7. doi: 10.1111/tri.12738. Epub 2016 Jan 15.
9
Lung transplantation using controlled donation after circulatory death donors: Trials and tribulations.
J Heart Lung Transplant. 2016 Jan;35(1):146-147. doi: 10.1016/j.healun.2015.10.004. Epub 2015 Nov 6.
10
Successful lung transplantation from a donation after cardiocirculatory death donor taking more than 120 minutes to cardiac arrest after withdrawal of life support therapies.
J Heart Lung Transplant. 2016 Feb;35(2):258-9. doi: 10.1016/j.healun.2015.10.010. Epub 2015 Oct 8.
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