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心脏循环死亡后供体与肺移植

Donors after cardiocirculatory death and lung transplantation.

作者信息

Inci Ilhan

机构信息

Department of Thoracic Surgery, University Hospital, University of Zurich, Zurich, Switzerland.

出版信息

J Thorac Dis. 2017 Aug;9(8):2660-2669. doi: 10.21037/jtd.2017.07.82.

Abstract

The number of patients actively awaiting lung transplantation (LTx) is more than the number of suitable donor lungs. The percentage of lung retrieval rate is lower when compared to other solid organs. The use of lungs from donation after cardiocirculatory death (DCD) donors is one of the options to avoid organ shortage in LTx. After extensive experimental research, clinical application of DCD donation is becoming wider. The results from most of the centers show at least equal survival rate compared to donors from brain death. This review paper will summarize experimental background and clinical experience from DCD donors.

摘要

积极等待肺移植(LTx)的患者数量超过了合适供肺的数量。与其他实体器官相比,肺获取率的百分比更低。使用心源性循环死亡(DCD)供体的肺是避免肺移植中器官短缺的选择之一。经过广泛的实验研究,DCD供体的临床应用正在变得更加广泛。大多数中心的结果显示,与脑死亡供体相比,生存率至少相当。这篇综述文章将总结DCD供体的实验背景和临床经验。

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