Secondary Metabolites from the Nematode-Trapping Fungus YMF1.03409.

As a representative nematode-trapping fungus, can capture and kill nematodes by producing traps, known as adhesive knobs. In this paper, the strain of YMF1.03409 was studied by means of medium screening, fermentation, and purification and identification of crude extracts. Eighteen compounds were obtained from YMF1.03409, including two new metabolites, nosporins C () and D (). The known metabolites were identified to be 3-chloro-4-methoxybenzaldehyde (), 3-chloro-4-methoxybenzoic acid (), 2-chloro-1-methoxy-4-(methoxymethyl)benzene (), 3-hydroxy-3-methyloxindole (), nicotinic acid (), succinic acid (), 3,4-dihydroxybutanoic acid (), 5'-O-methyladenosine (), uridine (), 2'-deoxyuridine (), thymidine (), 3-(phenylmethyl)-2,5-morpholinedione (), methyl-β-D-glucopyranoside (), 1,2-benzenedicarboxylic acid bis(2-methyl heptyl) ester (), β-sitosterol (), and 3β,6α-diol-stigmastane (). The bioactive assay showed that these compounds had no obvious nematicidal activity against the nematodes and .