Hwang William D, Mossa-Basha Mahmud, Andre Jalal B, Hippe Daniel S, Culbertson Scott, Anzai Yoshimi
From the Department of Radiology, University of Washington Medical Center, Seattle, WA.
J Comput Assist Tomogr. 2016 Mar-Apr;40(2):320-5. doi: 10.1097/RCT.0000000000000350.
Dual-energy computed tomography (DECT) allows image reconstruction along a spectrum of virtual monochromatic energy levels. We sought to determine the optimal energy level(s) for viewing supratentorial brain and posterior fossa and compare those to polychromatic conventional CT (CCT). Furthermore, we compared 2 groups scanned with separate DECT imaging protocols. In addition, we quantify the radiation dose of DECT versus CCT.
Forty-four nonacute patients underwent noncontrast DECT and recent CCT on the same scanner. Dual-energy CT images of the head were reconstructed at 5 keV intervals from 50 to 100 keV and randomized with CCT for blinded reader analysis. Evaluation of gray-white matter differentiation, posterior fossa artifact, and overall image noise was performed in consensus using a 5-point scale. In addition, the CTDIvol was compared with CCT examinations.
Optimal monochromatic viewing levels in evaluating gray-white matter differentiation were 50 to 55 keV and 50 to 60 keV, using regular-dose DECT (R-DECT) and low-dose DECT (L-DECT), respectively. The optimal levels for mitigating posterior fossa artifacts were 80 to 100 keV utilizing both R-DECT and L-DECT, whereas the optimal viewing levels for improved overall image noise were 60 to 65 keV and 65 to 70 keV for R-DECT and L-DECT, respectively. Readers favored both DECT techniques over CCT. The CTDIvol for DECT was 10% and 37% lower than CCT without a statistically significant reduction in image quality.
Optimized noncontrast DECT compared favorably to CCT, with a significant dose reduction benefit.
双能计算机断层扫描(DECT)能够沿一系列虚拟单色能量水平进行图像重建。我们试图确定观察幕上脑和后颅窝的最佳能量水平,并将其与多色传统CT(CCT)进行比较。此外,我们比较了采用不同DECT成像方案扫描的两组患者。另外,我们对DECT和CCT的辐射剂量进行了量化。
44例非急性患者在同一台扫描仪上接受了非增强DECT和近期的CCT检查。头部的双能CT图像在50至100 keV范围内以5 keV间隔重建,并与CCT随机排列,供盲法阅片者分析。采用5分制对灰白质区分、后颅窝伪影和整体图像噪声进行一致性评估。此外,将容积CT剂量指数(CTDIvol)与CCT检查进行比较。
在评估灰白质区分时,使用常规剂量DECT(R-DECT)和低剂量DECT(L-DECT)的最佳单色观察水平分别为50至55 keV和50至60 keV。减轻后颅窝伪影的最佳水平在R-DECT和L-DECT中均为80至100 keV,而改善整体图像噪声的最佳观察水平在R-DECT和L-DECT中分别为60至65 keV和65至70 keV。阅片者更青睐两种DECT技术而非CCT。DECT的CTDIvol比CCT低10%和37%,且图像质量无统计学意义的下降。
优化后的非增强DECT与CCT相比具有优势,有显著的剂量降低效益。