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美国不同社区白内障手术率及手术时机的地理差异。

Geographic Variation in the Rate and Timing of Cataract Surgery Among US Communities.

作者信息

Kauh Courtney Y, Blachley Taylor S, Lichter Paul R, Lee Paul P, Stein Joshua D

机构信息

Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor.

Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan, Ann Arbor2Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor.

出版信息

JAMA Ophthalmol. 2016 Mar;134(3):267-76. doi: 10.1001/jamaophthalmol.2015.5322.

Abstract

IMPORTANCE

Previous studies using data from the 1980s found relatively little geographic variation in cataract surgery rates across the United States. We do not know whether similar patterns hold true today, nor do we know the patient- and community-level factors that might explain any recent geographic variations in the rate and timing of cataract surgery.

OBJECTIVE

To assess the extent of geographic variation in patient age at initial cataract surgery and the age-standardized cataract surgery rate in a large group of insured US patients with cataracts.

DESIGN, SETTING, AND PARTICIPANTS: Retrospective cross-sectional study of 1 050 815 beneficiaries older than 40 years of age with cataracts who were enrolled in a nationwide managed-care network during the period from 2001 to 2011. The data analysis was started in 2014 and refined in 2015.

MAIN OUTCOMES AND MEASURES

Median age at initial cataract extraction, age-standardized cataract surgery rate, and time from initial diagnosis to first surgery for patients with cataracts were compared among 306 US communities. Multivariable regression modeling generated hazard ratios (HRs) with 95% CIs identifying factors associated with patients' likelihood of undergoing cataract surgery.

RESULTS

A total of 243 104 patients with cataracts (23.1%) underwent 1 or more surgical procedures (55.1% were female patients). Communities with the youngest and oldest patients at initial surgery differed in age by nearly 20 years (59.9-60.1 years in Lansing, Michigan, and Aurora, Illinois, vs 77.0-79.6 years in Marquette, Michigan; Rochester, New York; and Binghamton, New York). The highest age-standardized cataract surgery rate (37.3% in Lake Charles, Louisiana) was 5-fold higher than the lowest (7.5% in Honolulu, Hawaii). The median time from initial cataract diagnosis to date of first surgery ranged from 17 days (Victoria, Texas) to 367 days (Yakima, Washington). Compared with white patients, black patients had a 15% decreased hazard of surgery (HR, 0.85 [95% CI, 0.83-0.87]), while Latino patients (HR, 1.08 [95% CI, 1.05-1.10]) and Asian patients (HR, 1.09 [95% CI, 1.05-1.12]) had an increased hazard. For every 1° higher latitude, the hazard of surgery decreased by 1% (HR, 0.99 [95% CI, 0.98-0.99]). For every additional optometrist per 100 000 enrollees in a community, the hazard of surgery increased 0.1% (HR, 1.001 [95% CI, 1.001-1.001]).

CONCLUSIONS AND RELEVANCE

In recent years, patient age at first cataract surgery and the age-standardized surgery rate have varied considerably among some US communities. Future research should explore the extent to which such variations may affect patient outcomes.

摘要

重要性

以往利用20世纪80年代数据开展的研究发现,美国白内障手术率在地域上的差异相对较小。我们不清楚如今是否仍存在类似模式,也不清楚患者层面和社区层面的因素,这些因素可能解释近期白内障手术率及手术时机在地域上的差异。

目的

评估一大群有保险的美国白内障患者初次白内障手术时的患者年龄及年龄标准化白内障手术率在地域上的差异程度。

设计、设置和参与者:对2001年至2011年期间纳入全国性管理式医疗网络的1050815名40岁以上白内障患者进行回顾性横断面研究。数据分析于2014年开始,并于2015年完善。

主要结局和测量指标

比较美国306个社区白内障患者初次白内障摘除时的年龄中位数、年龄标准化白内障手术率以及初次诊断至首次手术的时间。多变量回归模型生成风险比(HR)及95%置信区间,以确定与患者接受白内障手术可能性相关的因素。

结果

共有243104名白内障患者(23.1%)接受了1次或更多次手术(55.1%为女性患者)。初次手术时患者年龄最小和最大的社区,年龄相差近20岁(密歇根州兰辛市和伊利诺伊州奥罗拉市为59.9 - 60.1岁,而密歇根州马凯特市、纽约州罗切斯特市和纽约州宾厄姆顿市为77.0 - 79.6岁)。年龄标准化白内障手术率最高的是路易斯安那州查尔斯湖市(37.3%),比最低的夏威夷州檀香山(7.5%)高出5倍。初次白内障诊断至首次手术的时间中位数从17天(得克萨斯州维多利亚市)到367天(华盛顿州亚基马市)不等。与白人患者相比,黑人患者手术风险降低15%(HR,0.85 [95% CI,0.83 - 0.87]),而拉丁裔患者(HR,1.08 [95% CI,1.05 - 1.10])和亚裔患者(HR,1.09 [95% CI,1.05 - 1.12])手术风险增加。纬度每升高1°,手术风险降低1%(HR,0.99 [95% CI,0.98 - 0.99])。社区中每10万名参保人每增加一名验光师,手术风险增加0.1%(HR,1.001 [95% CI,1.001 - 1.001])。

结论及相关性

近年来,美国一些社区初次白内障手术时的患者年龄及年龄标准化手术率差异很大。未来研究应探讨这种差异可能在多大程度上影响患者预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b22f/5767078/d944ba69eb32/nihms816535f1.jpg

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